20 papers · ranked by Valyu relevance
Eike-Christian Wamhoff, Larance Ronsard, Jared Feldman, Blake M. Hauser + 8 more
Multivalent antigen display is a well-established design principle to enhance humoral immunity elicited by subunit vaccines. Protein-based virus-like particles (VLPs) are an important vaccine platform that implements this principle but also contain thymus-dependent off-target epitopes, thereby generating neutralizing…
Guilherme M. Lima, Alexey Atrazhev, Susmita Sarkar, Mirat Sojitra + 4 more
Phage display links phenotype of displayed polypeptides with DNA sequence in phage genome and offers a universal method for discovery of proteins with novel properties. Injection of phage-displayed libraries in living organisms further provides a unique and powerful approach to optimize biochemical, pharmacological and…
Ana R. Humpierre, Yanira Méndez, Ahyoung Kim, Michael Niemeyer + 8 more
The ability to conjugate multiple molecules to a protein is of great interest for pharmaceutical and vaccine development, especially if this can be achieved in a one-pot procedure. Multicomponent reactions are powerful procedures that allow the assembly of complex constructs incorporating at least three molecular…
Linlin Gu, Zan C. Li, Alexandre Krendelchtchikov, Valentina Krendelchtchikova + 3 more
'Valentina Krendelchtchikova' 'Hongju Wu' 'Qiana L. Matthews' 'Ernesto T. A. Marques'] Adenoviral vectors have been used for a variety of vaccine applications including cancer and infectious diseases. Traditionally, Ad-based vaccines are designed to express antigens through transgene expression of a given antigen. For…
Xinyu Ning, Darshita Budhadev, Sara Pollastri, Inga Nehlmeier + 8 more
Multivalent lectin-glycan interactions (MLGIs) are widespread and vital for biology, making them attractive therapeutic tar-gets. Unfortunately, the structural and biophysical mechanisms of several key MLGIs remain poorly understood, limiting our ability to design spatially matched glycoconjugates as potent…
Bence Bruncsics, Wesley J. Errington, Casim A. Sarkar
Arising through multiple binding elements, multivalency can specify the avidity, duration, cooperativity, and selectivity of biomolecular interactions, but quantitative prediction and design of these properties has remained challenging. Here we present MVsim, an application suite built around a configurational network…
Bing Xu, Jingwei Chen, Ziyi Ding, Jianwei Hu + 3 more
'Haizeng Li' 'Huanlei Wang'] Electrochromic technology has witnessed numerous achievements in recent years both in research and commercialization. Electrochromic devices (ECD) based on different electrochemical mechanism have been developed for various applications, ranging from smart windows, thermal management, rear…
Authors not listed
Multivalent lectin-glycan interactions (MLGIs) are vital for viral infection, cell-cell communication and regulation of immune responses. Their structural and biophysical data are thus important, not only for providing insights into their underlying mechanisms but also for designing potent glycoconjugate therapeutics…
James Hooper, Darshita Budhadev, Dario Fernandez Ainaga Ainaga, Nicole Hondow + 2 more
Multivalent lectin-glycan interactions (MLGIs) are widespread and vital for biology, and also hold the key to many therapeutic applications. However, the underlying structural and biophysical mechanisms for many MLGIs remain poorly understood, limiting our ability to design glycoconjugates that can potently target…
Seokyeong Lee, Jong Woong Park, Jihye Jang, Jin Woo Oh + 9 more
'Jioh Yoo' 'Jong Gun Jung' 'Hyowon Han' 'Wei Jiang' 'Chang Eun Lee' 'Jungwon Yoon' 'Kaiying Zhao' 'Cheolmin Park'] Title: Highlights 1. A rewritable triple-mode light-emitting display (RE-TriLED) was fabricated, enabled by stimuli-interactive fluorescence (FL), room-temperature phosphorescence (RTP), and…
Amelia C. Wood, Edwin C. Johnson, Ram R. R. Prasad, Mark V. Sullivan + 4 more
Peptides are important biomarkers for a range of diseases, however distinguishing different amino-acid sequences using artificial receptors remains a major challenge in biomedical sensing. Here we present a new approach to creating highly selective recognition surfaces using phage display biopanning against…
Ryuji Hirayama, Atsushi Shiraki, Makoto Naruse, Shinichiro Nakamura + 4 more
'Hirotaka Nakayama' 'Takashi Kakue' 'Tomoyoshi Shimobaba' 'Tomoyoshi Ito'] This is the first study to demonstrate that colour transformations in the volume of a photochromic material (PM) are induced at the intersections of two control light channels, one controlling PM colouration and the other controlling…
Felix Heide, James Gregson, Gordon Wetzstein, Ramesh Raskar + 1 more
'Wolfgang Heidrich'] Abstract: Compressive displays are an emerging technology exploring the co-design of new optical device configurations and compressive computation. Previously, research has shown how to improve the dynamic range of displays and facilitate high-quality light field or glasses-free 3D image synthesis.…
Ryuji Hirayama, Tomotaka Suzuki, Tomoyoshi Shimobaba, Atsushi Shiraki + 4 more
'Atsushi Shiraki' 'Makoto Naruse' 'Hirotaka Nakayama' 'Takashi Kakue' 'Tomoyoshi Ito'] In this study, a method to construct a full-colour volumetric display is presented using a commercially available inkjet printer. Photoreactive luminescence materials are minutely and automatically printed as the volume elements, and…
Suman Halder, Yunho Shin, Yidan Peng, Long Wang + 7 more
'Paul Schmalenberg' 'Guangkui Qin' 'Yuxi Gao' 'Ercan M. Dede' 'Deng‐Ke Yang' 'Sean P. Rodrigues'] - 1. Department of Physics, Kent State University, Kent, OH 44242 - 2. Advanced Materials and Liquid Crystal Institute, Kent State University, Kent, OH 442422 - 3. Central Research Institute, BOE Technology Group Co.…
Matthew Isaacson, Lisa Ferguson, Frank Loesche, Ishani Ganguly + 5 more
Visual stimulation of animals in the laboratory is a powerful technique for studying sensory control of complex behaviors. Since commercial displays are optimized for human vision, we established a novel display system based on custom-built modular LED panels that provides millisecond refresh, precise synchronization…
Zeyu Yan, Hsuanling Lee, Liang He, Huaishu Peng
We present a pipeline for printing interactive and always-on magnetophoretic displays using affordable Fused Deposition Modeling (FDM) 3D printers. Using our pipeline, an end-user can convert the surface of a 3D shape into a matrix of voxels. The generated model can be sent to an FDM 3D printer equipped with an…
Do Yoon Kim, Mi-Ji Kim, Gimin Sung, Jeong-Yun Sun
Displays play a significant role in delivering information and providing visual data across all media platforms. Among displays, the prominence of reflective displays is increasing, in the form of E-paper, which has features distinct from emissive displays. These unique features include high visibility under daylight…
Yuteng Wu, M. Teresa Bertran, Dhira Joshi, Sarah Maslen + 2 more
Photoaffinity labelling is a promising method for studying protein-ligand interactions. However, obtaining a specific crosslinker can require significant optimisation. We report a novel mRNA display strategy, photocrosslinking-RaPID (XL-RaPID), and exploit its ability to accelerate the discovery of cyclic peptides that…
Cyril Hilsum
This paper describes the history and science behind the development of modern flat-panel displays, and assesses future trends. Electronic displays are an important feature of modern life. For many years the cathode ray tube, an engineering marvel, was universal, but its shape was cumbersome and its operating voltage…