24 papers · ranked by Valyu relevance
Shilpa Chakravartula, Premananda Indic, Bala Sundaram, Timothy Killingback + 1 more
'Timothy Killingback' 'Jun Ma'] Local synchronization, both prolonged and transient, of oscillatory neuronal behavior in cortical networks plays a fundamental role in many aspects of perception and cognition. Here we study networks of Hindmarsh-Rose neurons with a new type of adaptive coupling, and show that these…
Zahra G. Esfahani, Leonardo L. Gollo, Alireza Valizadeh
Time delay is a general feature of all interactions. Although the effects of delayed interaction are often neglected when the intrinsic dynamics is much slower than the coupling delay, they can be crucial otherwise. We show that delayed coupled neuronal networks support transitions between synchronous and asynchronous…
Rafael R. Borges, Fernando S. Borges, Ewandson L. Lameu, Paulo R. Protachevicz + 7 more
'Paulo R. Protachevicz' 'Kelly C. Iarosz' 'Iberê L. Caldas' 'Ricardo L. Viana' 'Elbert E. N. Macau' 'Murilo S. Baptista' 'Celso Grebogi' 'Antônio M. Batista'] Brain plasticity, also known as neuroplasticity, is a fundamental mechanism of neuronal adaptation in response to changes in the environment or due to brain…
Alexandra S Landsman, Ira B Schwartz
The dynamics of three mutually coupled cortical neurons with time delays in the coupling are explored numerically and analytically. The neurons are coupled in a line, with the middle neuron sending a somewhat stronger projection to the outer neurons than the feedback it receives, to model for instance the relay of a…
Epaminondas Rosa Jr., Samuel Krueger
Synchronization of neurons remains a topic of great interest due in part to practical implications of relevance to desirable as well as to undesirable states. Neural synchrony can be related, for instance, to healthy activity as in the case of the various stages of sleep , but can also be related to pathological…
Zahra Ghasemi Esfahani, Alireza Valizadeh, Matjaz Perc
A novel proposal for the zero-lag synchronization of the delayed coupled neurons, is to connect them indirectly via a third relay neuron. In this study, we develop a Poincaré map to investigate the robustness of the synchrony in such a relay system against inhomogeneity in the neurons and synaptic parameters. We show…
Ezekiel Williams, Aaron R. Shifman, John E. Lewis
Synchronization is a fundamental property of biological neural networks, playing a mechanistic role in both healthy and disease brain states. The medullary pacemaker nucleus of the weakly electric fish is a synchronized network of high-frequency neurons, weakly coupled via gap junctions. Synchrony in the pacemaker is…
Gorana Mijatovic, Tatjana Loncar-Turukalo, Nebojsa Bozanic, Luca Faes
Multiple methods have been developed in an attempt to quantify stimulus-induced neural coordination and to understand internal coordination of neuronal responses by examining the synchronization phenomena in neural discharge patterns. In this work we propose a novel approach to estimate the degree of concomitant firing…
Roni Vardi, Amir Goldental, Shoshana Guberman, Alexander Kalmanovich + 2 more
'Hagar Marmari' 'Ido Kanter'] A classical view of neural coding relies on temporal firing synchrony among functional groups of neurons, however, the underlying mechanism remains an enigma. Here we experimentally demonstrate a mechanism where time-lags among neuronal spiking leap from several tens of milliseconds to…
Roni Vardi, Amir Goldental, Shoshana Guberman, Alexander Kalmanovich + 2 more
'Hagar Marmari' 'Ido Kanter'] A classical view of neural coding relies on temporal firing synchrony among functional groups of neurons; however the underlying mechanism remains an enigma. Here we experimentally demonstrate a mechanism where time-lags among neuronal spiking leap from several tens of milliseconds to…
Fernando S. Borges, Paulo R. Protachevicz, Ewandson L. Lameu, Robson Conrado Bonetti + 3 more
'Robson Conrado Bonetti' 'Maurı́cio S. Baptista' 'Antônio M. Batista' 'Iberê L. Caldas'] We have studied neuronal synchronisation in a random network of adaptive exponential integrate-and-fire neurons. We study how spiking or bursting synchronous behaviour appears as a function of the coupling strength and the…
Jieqiong Xu, Quan Yuan, Huiying Chen
Pre-Bötzinger complex (PBC) is a necessary condition for the generation of respiratory rhythm. Due to the existence of synaptic gaps, delay plays a key role in the synchronous operation of coupled neurons. In this study, the relationship between synchronization and correlation degree is established for the first time…
Xiaoyue Wu, Congping lin, Yiwei Zhang
Neuronal network synchronization has received wide interests. Network connection structure is known to play a key role in its synchronization. In the present manuscript, we study the influence of initial membrane potentials together with network topology on bursting synchronization, in particular the sequential spiking…
Gualberto Solís-Perales, Jairo Sánchez Estrada
A model of time-dependent structural plasticity for the synchronization of neuron networks is presented. It is known that synchronized oscillations reproduce structured communities, and this synchronization is transient since it can be enhanced or suppressed, and the proposed model reproduces this characteristic. The…
Javier Used, Jesús M. Seoane, Irina Bashkirtseva, Lev Ryashko + 1 more
neurons Authors: ['Javier Used' 'Jesús M. Seoane' 'Irina Bashkirtseva' 'Lev Ryashko' 'Miguel A. F. Sanjuán'] Synchronization dynamics is a phenomenon of great interest in many fields of science. One of the most important fields is neuron dynamics, as synchronization in certain regions of the brain is related to some of…
Roni Vardi, Reut Timor, Shimon Marom, Micha Abeles + 1 more
We show that the unavoidable increase in neuronal response latency to ongoing stimulation serves as a nonuniform gradual stretching of neuronal circuit delay loops and emerges as an essential mechanism in the formation of various types of neuronal timers. Synchronization emerges as a transient phenomenon without…
Joel Zirkle, Leonid L Rubchinsky
Neural synchrony in the brain is often present in an intermittent fashion, i.e., there are intervals of synchronized activity interspersed with intervals of desynchronized activity. A series of experimental studies showed that this kind of temporal patterning of neural synchronization may be very specific and may be…
Mohammad Amin Fakharian, Elijah A. Taeckens, Alexander N. Vasserman, Alden M. Shoup + 1 more
We tend to think of neurons as either excitatory or inhibitory, but certain neurons chemically inhibit their downstream targets while electrically exciting each other. For example, in the cerebellum, molecular layer interneurons type 1 (MLI1s) inhibit Purkinje cells (P-cells) via release of GABA but promote spiking in…
Sarang Saini, Rishikesh Narayanan
Information flow and temporal coding in cortical circuits depend critically on the reliable transmission of precisely timed synchronous spike patterns. Although cortical assemblies achieve such transmission despite pronounced intrinsic heterogeneities and stochastic high-conductance states, the mechanisms underlying…
Rafael R. Borges, Fernando S. Borges, Ewandson L. Lameu, Antônio M. Batista + 4 more
'Antônio M. Batista' 'Kelly C. Iarosz' 'Iberê L. Caldas' 'Ricardo L. Viana' 'Miguel A. F. Sanjuán'] In this paper, we study the effects of spike timing-dependent plasticity on synchronisation in a network of Hodgkin-Huxley neurons. Neuron plasticity is a flexible property of a neuron and its network to change…
Holger Finger, Richard Gast, Christian Gerloff, Andreas K. Engel + 1 more
Communication and dynamic routing play important roles in the human brain to facilitate flexibility in task solving and thought processes. Here, we present a new network perturbation methodology and a corresponding analysis method to investigate and demonstrate the dynamic switching between different excitable pathways…
Afsaneh Taheri Kal-Koshvandi
We present the first light-free, genetically minimal platform for spatiotemporally resolved proximity labeling across five neuronal compartments—synaptic, nuclear, endosomal, mitochondrial, and activity-dependent microdomains. A covalent "catalyst–luciferase sandwich" architecture site-specifically conjugates five…
Authors not listed
Real-world datasets in chemical engineering and bioengineering processes--such as those from catalytic reactors, multiphase flows, polymerization reactors, bioreactors, and clinical trials--can often be unlabelled or disorganized, rendering the training of existing supervised learning models ineffective at learning the…
Yuanmo Wang, Ajay Pradhan, Pankaj Gupta, Jörg Hanrieder + 2 more
Acetylcholine (ACh) is a critical neurotransmitter influencing various neurophysiological functions. Despite its significance, there is a lack of quantitative methods with adequate spatiotemporal resolution for recording single exocytotic efflux of ACh. In this study, we present an ultrafast amperometric ACh biosensor…