20 papers · ranked by Valyu relevance
Kostas Nizamis, Alkinoos Athanasiou, Sofia Almpani, Christos Dimitrousis + 2 more
'Christos Dimitrousis' 'Alexander Astaras' 'Dongwook Rha'] Recent advances in the field of neural rehabilitation, facilitated through technological innovation and improved neurophysiological knowledge of impaired motor control, have opened up new research directions. Such advances increase the relevance of existing…
Kenji Kansaku
The impaired brain is often difficult to restore, owing to our limited knowledge of the complex nervous system. Accumulating knowledge in systems neuroscience, combined with the development of innovative technologies, may enable brain restoration in patients with nervous system disorders that are currently untreatable.…
James Wright, Vaughan G. Macefield, André van Schaik, Jonathan C. Tapson
'Jonathan C. Tapson'] It has been widely recognized that closed-loop neuroprosthetic systems achieve more favorable outcomes for users then equivalent open-loop devices. Improved performance of tasks, better usability, and greater embodiment have all been reported in systems utilizing some form of feedback. However…
Kumar J. Jyothish, Subhankar Mishra
The field of robotics is a quickly evolving feat of technology that accepts contributions from various genres of science. Neuroscience, Physiology, Chemistry, Material science, Computer science, and the wide umbrella of mechatronics have all simultaneously contributed to many innovations in the prosthetic applications…
Mitsuhiro Hayashibe, David Guiraud, Jose L. Pons, Dario Farina
Neuroprosthetics is an interdisciplinary field of study that comprises neuroscience, computer science, physiology, and biomedical engineering. Each of these areas contributes to finally enhance the functionality of neural prostheses for the substitution or restoration of motor, sensory or cognitive funtions that might…
Anh Tuan Nguyen, Jian Xu, Ming Jiang, Diu Khue Luu + 9 more
While prosthetic hands with independently actuated digits have become commercially available, state-of-the-art human-machine interfaces (HMI) only permit control over a limited set of grasp patterns, which does not enable amputees to experience sufficient improvement in their daily activities to make an active…
Gunther Eysenbach, Amine Korchi, Giacomo Valle
Decades of technological developments have populated the field of brain-machine interfaces and neuroprosthetics with several replacement strategies, neural modulation treatments, and rehabilitation techniques to improve the quality of life for patients affected by sensory and motor disabilities. This field is now…
S. Buccelli, Y. Bornat, I. Colombi, M. Ambroise + 13 more
Recent advances in neurotechnology allow neurological impairments to be treated or reduced by brain machine interfaces and neuroprostheses. To develop energy-efficient and real-time capable devices, neuromorphic computing systems are envisaged as the core of next-generation ‘neurobiohybrid’ systems for brain repair. We…
Retnaningsh Retnaningsih, Agus Budiyono, Rifky Ismail, Dodik Tugasworo + 3 more
'Dodik Tugasworo' 'Rivan Danuaji' 'Syahrul Syahrul' 'Jerry Gunawan'] † Department of Neurology, Kariadi Hospital, Indonesia. ‡ Indonesia Center for Technology Empowerment (ICTE), Indonesia. ‡‡ Centerfor Biomechanics Biomaterials Biomechatronics and Biosignal Processing, Diponegoro University, Indonesia. £ Faculty of…
Abdelkader Nasreddine Belkacem, Nuraini Jamil, Sumayya Khalid, Fady Alnajjar
'Fady Alnajjar'] Emerging brain technologies have significantly transformed human life in recent decades. For instance, the closed-loop brain-computer interface (BCI) is an advanced software-hardware system that interprets electrical signals from neurons, allowing communication with and control of the environment. The…
William R. Muirhead, Hugo Layard Horsfall, Christine Aicardi, Jacques Carolan + 4 more
'Jacques Carolan' 'Harith Akram' 'Anne Vanhoestenberghe' 'Andreas T. Schaefer' 'Hani J. Marcus'] Implanted cortical neuroprosthetics (ICNs) are medical devices developed to replace dysfunctional neural pathways by creating information exchange between the brain and a digital system which can facilitate interaction with…
Laura Becerra-Fajardo, Marc Oliver Krob, Jesus Minguillon, Camila Rodrigues + 6 more
Implantable neuroprostheses consisting of a central electronic unit wired to electrodes benefit thousands of patients worldwide. However, they present limitations that restrict their use. Those limitations, which are more adverse in motor neuroprostheses, mostly arise from their bulkiness and the need to perform…
Rebecca C. Felsheim, David J. Sly, Stephen J. O’Leary, Mathias Dietz
Neuroprosthetics, such as cochlear implants or deep brain stimulators, can restore parts of the function of an impaired system. To improve such prosthetics, a detailed understanding of the electrical stimulation of nerve fibers is required. This knowledge can best be represented by computational models of the process.…
Xuan-The Tran
Millions of individuals worldwide suffer from sensory and communication deficits caused by neurodegenerative diseases, stroke, or trauma. Brain-computer interfaces (BCIs) offer a promising avenue for sensory and motor restoration. However, the scientific literature remains highly fragmented between invasive…
Jovana J. Belić, Aldo A. Faisal
The only way we can interact with the world is through movements, and our primary interactions are via the hands, thus any loss of hand function has immediate impact on our quality of life. However, to date it has not been systematically assessed how coordination in the hand’s joints affects every day actions. This is…
Catarina Dias, Domingos Castro, Miguel Aroso, João Ventura + 1 more
Neurons are specialized cells in information transmission and information processing. Following this, many neurologic disorders are directly linked not to cellular viability/homeostasis issues but rather to specific anomalies in electrical activity dynamics. Acknowledging this fact, therapeutic strategies based on…
Jens Christian Claussen, Ulrich Hofmann
Modeling of consciousness-related phenomena and neuroengineering are fields that are rapidly growing together. We review recent approaches and developments and point out some promising directions of future research: Understanding the dynamics of consciousness states and associated oscillations, pathological…
Max Talanov, Jordi Vallverdú, Andrew Adamatzky, Alexander Toschev + 17 more
'Alina Suleimanova' 'Alexey Leukhin' 'Ann Posdeeva' 'Yulia Mikhailova' 'Alice Rodionova' 'A. N. Mikhaylov' 'Alexantrou Serb' 'Sergey Shchanikov' 'Svetlana A. Gerasimova' 'Mohammad Mahdi Dehshibi' 'Alexander E. Hramov' 'Victor Kazantsev' 'Tatyana Tsoy' 'Evgeni Magid' 'Igor Lavrov' 'Victor Erokhin' 'Kevin Warwick'] Max…
Rebecca Howell, Rinco Wang, David McDonald, David Spiegel
We present the application of Angiopep-2 as a molecular degrader of extracellular proteins (MoDE) promoting target protein removal by both transcytosis and lysosomal degradation mechanisms in brain endothelial cells. The accumulation of pathogenic proteins is a hallmark of many neurodegenerative diseases, and removal…
Authors not listed
Carbon fiber has become the standard electrode material to study neuronal communication. For techniques such as single-cell amperometry at synapses and intracellular recordings of neurotransmitters in secretory vesicles, nanometric electrodes are required. The smaller electrode dimension also offers the added benefit…