19 papers · ranked by Valyu relevance
Binghao Yang, Guangzong Chen
The foundation of cognitive flexibility and higher-order intelligence lies in the functional structure and activity of brain networks, which can be dynamically configured by both external environments and internal states. However, decoding these dynamics from high-dimensional neural data remains a challenge. In this…
Selene Schintu, Catherine A. Cunningham, Michael Freedberg, Paul Taylor + 3 more
Hemispatial neglect is thought to result from disruption of interhemispheric equilibrium. Right hemisphere lesions deactivate the right frontoparietal network and hyperactivate the left via release from interhemispheric inhibition. Support for this theory comes from neuropsychological evidence as well as transcranial…
Rocco Chiou, R. Austin Benn, Robert Scholz, Wei Wei + 4 more
The cerebral cortex forms a structured landscape in which the location of brain regions shapes their cognitive functions. Based on this cognitive topography, brain regions are not isolated modules but embedded within a macroscale terrain where both cortical geometry and connectivity jointly shape cognition. If cortical…
Emil H. J. Nijhuis, Anne-Marie van Cappellen van Walsum, David G. Norris, Michal Zochowski
'David G. Norris' 'Michal Zochowski'] Hubs within the neocortical structural network determined by graph theoretical analysis play a crucial role in brain function. We mapped neocortical hubs topographically, using a sample population of 63 young adults. Subjects were imaged with high resolution structural and…
Stefano Diomedi, Francesco Edoardo Vaccari, Kostas Hadjidimitrakis, Patrizia Fattori + 1 more
The posterior parietal cortex (PPC) plays a central role in sensorimotor control, performing visuomotor transformations, supporting planning, and providing visual feedback. However, it is unknown how the neural populations in different PPC areas organize their activity during this process. It has been proposed that PPC…
Marshall A Dalton, Eleanor A Maguire
Title: Highlights 1. • We consider internal representations of the world in the form of scenes. 2. • The anterior medial hippocampus is implicated in scene-based cognition. 3. • This region contains the pre/parasubiculum. 4. • The pre/parasubiculum is a primary target of a major visuospatial processing system. 5. • The…
G. Dumas, Q. Moreau, E. Tognoli, J.A.S. Kelso
How does the brain allow us to interact with others, and above all how does it handle situations when the goals of the interactors overlap (i.e. cooperation) or differ (i.e. competition)? Social neuroscience has already provided some answers to these questions but has tended to treat high-level, cognitive…
L. Musa, A. Ghaderi, Y. Chen, J.D Crawford
Humans can be instructed to ignore visual cues or use them as landmarks for aiming movements (54), but it is not known how such allocentric cues interact with egocentric target codes and general planning activity to influence cortical network properties. To answer these questions, we applied graph theory analysis (GTA)…
Zhilei Xu, Mingrui Xia, Xindi Wang, Xuhong Liao + 2 more
Macroscopic functional connectomic analyses have identified sets of densely connected regions in the human brain, known as connectome hubs, which play a vital role in understanding network communication, cognitive processing, and brain disorders. However, anatomical locations of functional connectome hubs are largely…
Marvin Jüchtern, Usman Jawed Shaikh, Svenja Caspers, Ferdinand Binkofski
'Ferdinand Binkofski'] Title: Abstract Networks in the parietal and premotor cortices enable essential human abilities regarding motor processing, including attention and tool use. Even though our knowledge on its topography has steadily increased, a detailed picture of hemisphere-specific integrating pathways is still…
Gina F. Humphreys, Rebecca L. Jackson, Matthew A. Lambon Ralph
The parietal cortex (PC) is implicated in a confusing myriad of different cognitive processes/tasks. Consequently, understanding the nature and organisation of the core underlying neurocomputations is challenging. According to the Parietal Unified Connectivity-biased Computation (PUCC) model two properties underpin PC…
Zhiguo Luo, Ling‐Li Zeng, Hui Shen, Dewen Hu
The frequency-specific coupling mechanism of the functional human brain networks underpins its complex cognitive and behavioral functions. Nevertheless, it is not well unveiled what are the frequency-specific subdivisions and network topologies of the human brain. In this study, we estimated functional connectivity of…
Xindi Wang, Qixiang Lin, Mingrui Xia, Yong He
Human brain structural networks contain sets of centrally embedded hub regions that enable efficient information communication. However, it remains largely unknown about categories of structural brain hubs and their microstructural, functional and cognitive characteristics as well as contributions to individual…
Suhas Vijayakumar, Jerome Sallet, Lennart Verhagen, Davide Folloni + 2 more
Resting state functional connectivity has been promoted as a promising tool for creating cortical maps that show remarkable similarity to those established by invasive histological methods. While this tool has been largely used to identify and map cortical areas, its true potential in the context of studying…
John-Ross Rizzo, Maryam Hosseini, Eric A. Wong, Wayne E. Mackey + 6 more
'James K. Fung' 'Edmond Ahdoot' 'Janet C. Rucker' 'Preeti Raghavan' 'Michael S. Landy' 'Todd E. Hudson'] Acute and chronic disease processes that lead to cerebral injury can often be clinically challenging diagnostically, prognostically, and therapeutically. Neurodegenerative processes are one such elusive diagnostic…
Richard Jarrett Rushmore, Sylvain Bouix, Marek Kubicki, Yogesh Rathi + 2 more
'Edward Yeterian' 'Nikos Makris'] Comparative structural neuroanatomy is a cornerstone for understanding human brain structure and function. A parcellation framework that relates systematically to fundamental principles of histological organization is an essential step in generating structural comparisons between…
Alistair Perry, Wei Wen, Anton Lord, Anbupalam Thalamuthu + 2 more
'Perminder S. Sachdev' 'Michael Breakspear'] Investigations of the human connectome have elucidated core features of adult structural networks, particularly the crucial role of hub-regions. However, little is known regarding network organisation of the healthy elderly connectome, a crucial prelude to the systematic…
Seung Suk Kang, Joseph S. Bodenheimer, Tracey Butler
The claustrum (Cl) is a thin grey matter structure located in the center of each brain hemisphere. Cl has been hypothesized as a central hub of the brain for multisensory/sensorimotor integration, consciousness, and attention. Accumulating evidence has suggested that Cl might be important in the development of severe…
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Molecular mechanisms governing initiation steps of the assembly of thousands of endogenous multi-protein complexes (EMCs) remain incompletely understood. Here, multiple lines of observations are reported reflecting the biological functions-aligned initiation sequence of hybrid assembly pathways (HAPs) of EMCs. HAPs…