21 papers · ranked by Valyu relevance
Binghao Yang, Guangzong Chen
The foundation of cognitive flexibility and higher-order intelligence lies in the functional structure and activity of brain networks, which can be dynamically configured by both external environments and internal states. However, decoding these dynamics from high-dimensional neural data remains a challenge. In this…
Rocco Chiou, R. Austin Benn, Robert Scholz, Wei Wei + 4 more
The cerebral cortex forms a structured landscape in which the location of brain regions shapes their cognitive functions. Based on this cognitive topography, brain regions are not isolated modules but embedded within a macroscale terrain where both cortical geometry and connectivity jointly shape cognition. If cortical…
Stefano Diomedi, Francesco Edoardo Vaccari, Kostas Hadjidimitrakis, Patrizia Fattori + 1 more
The posterior parietal cortex (PPC) plays a central role in sensorimotor control, performing visuomotor transformations, supporting planning, and providing visual feedback. However, it is unknown how the neural populations in different PPC areas organize their activity during this process. It has been proposed that PPC…
Zhilei Xu, Mingrui Xia, Xindi Wang, Xuhong Liao + 2 more
Macroscopic functional connectomic analyses have identified sets of densely connected regions in the human brain, known as connectome hubs, which play a vital role in understanding network communication, cognitive processing, and brain disorders. However, anatomical locations of functional connectome hubs are largely…
Hannah Clarke, Eirini Messaritaki, Stavros I. Dimitriadis, Claudia Metzler-Baddeley
Replicator dynamics identified hubs consistent across the individual risk factor groups. Individuals with no FH (N = 104) had hubs located in the left and right Rolandic operculum, right inferior parietal gyrus, left angular gyrus, and right Heschl's gyrus, whereas individuals with a positive FH (N = 59) had hubs at…
L. Musa, A. Ghaderi, Y. Chen, J.D Crawford
Humans can be instructed to ignore visual cues or use them as landmarks for aiming movements (54), but it is not known how such allocentric cues interact with egocentric target codes and general planning activity to influence cortical network properties. To answer these questions, we applied graph theory analysis (GTA)…
Marvin Jüchtern, Usman Jawed Shaikh, Svenja Caspers, Ferdinand Binkofski
'Ferdinand Binkofski'] Title: Abstract Networks in the parietal and premotor cortices enable essential human abilities regarding motor processing, including attention and tool use. Even though our knowledge on its topography has steadily increased, a detailed picture of hemisphere-specific integrating pathways is still…
Ryo Ishibashi, Gina Humphreys, Ajay Halai, Azumi Tanabe-Ishibashi + 2 more
Classical models of tool knowledge and use are centred on dorsal and ventral parietal pathways. Theories of semantic cognition implicate a “hub-and-spoke” network, centred on the anterior temporal lobe (ATL), that underpins all concepts including tools. Despite their prominence, the two theoretical frameworks have…
Ana Coelho, Ricardo Magalhães, Pedro S. Moreira, Liliana Amorim + 5 more
Connectivity-based parcellation (CBP) methods are used to define homogenous and biologically meaningful parcels or nodes-the foundations of brain network fingerprinting-by grouping voxels with similar patterns of brain connectivity. However, we still lack a gold standard method and the use of CBPs to study the aging…
Jung Uk Kang, Eric Mooshagian, Lawrence H. Snyder
Many studies infer the role of neurons by asking what information can be decoded from their activity or by observing the consequences of perturbing their activity. An alternative approach is to consider information flow between neurons. We applied this approach to the Parietal Reach Region (PRR) and the Lateral…
Emiliano Bruner, Alexandra Battaglia-Mayer, Roberto Caminiti
Traditional and new disciplines converge in suggesting that the parietal lobe underwent a considerable expansion during human evolution. Through the study of endocasts and shape analysis, paleoneurology has shown an increased globularity of the braincase and bulging of the parietal region in modern humans, as compared…
Sepehr Gourabi, Masoud Lotfalipour, Reza Khosrowabadi, Gholamreza Jafari
Structural Balance Theory Authors: ['Sepehr Gourabi' 'Masoud Lotfalipour' 'Reza Khosrowabadi' 'Gholamreza Jafari'] Working memory plays a crucial role in various aspects of human life. Therefore, it has been an area of interest in different research studies, especially neuroscience. The neuroscientists investigating…
Olga Boukrina, Peii Chen, Vincent P. Clark
Functional disability due to spatial neglect hinders recovery in up to 30% of stroke survivors. Prism adaptation treatment (PAT) may alleviate the disabling consequences of spatial neglect, but we do not yet know why some individuals show much better outcomes following PAT than others. The goal of this scoping review…
Artem Lensky
This study investigates EEG as a potential early biomarker by applying deep learning techniques to resting-state EEG recordings from 31 subjects (15 with PD and 16 healthy controls). EEG signals underwent preprocessing to remove tremor artifacts before classification with CNNs using wavelet-based electrode triplet…
Supriya Bordoloi, Cota Navin Gupta, Shyamanta M. Hazarika
—This study investigates the causal neural dynamics by which affordance representations influence action language comprehension. In this study, 18 participants observed stimuli displayed in two conditions during the experiment: text-only (e.g., 'Hit with a hammer') and video+text (visual clips with matching phrases).…
Richard T Ibitoye, Emma-Jane Mallas, Niall J Bourke, Diego Kaski + 2 more
'Adolfo M Bronstein' 'David J Sharp'] Title: Abstract Area OP2 in the posterior peri-sylvian cortex has been proposed to be the core human vestibular cortex. We investigated the functional anatomy of OP2 and adjacent areas (OP2+) using spatially constrained independent component analysis (ICA) of functional magnetic…
Jung Uk Kang, Lawrence H. Snyder, Eric Mooshagian
Inter-areal communication is crucial for brain function. Given the largely contralateral organization of the brain, bimanual coordination likely involves interactions across the two cerebral hemispheres for motor planning and execution. The parietal reach region (PRR) is an early node in the sensorimotor transformation…
Guttmann-Flury, Eva, Zhao, Jian + 2 more
— EEG-based Brain-Computer Interfaces (BCIs) frequently face spatial specificity limitations in detecting singletrial P300 potentials, a neurophysiological hallmark leveraged for both BCI control and neurodegenerative disease diagnostics. We present a novel framework combining eLORETA source localization with…
Carter Sale, Marco Coraggio, Mengsen Zhang, Michael J. Richardson
Network control theory applied to structural connectomes typically ranks brain regions as candidate driver nodes by their structural connectivity strength, and evaluates performance through scalar control energy. We test whether this framing captures the most relevant information about how driver-node selection shapes…
Chayanin Tangwiriyasakul, Pedro Borges, Guilherme Pombo, Stefano Moriconi + 8 more
'Stefano Moriconi' 'Michael S. Elmalem' 'Paul Wright' 'Yee‐Haur Mah' 'Jane Maryam Rondina' 'Robert J. Gray' 'Sébastien Ourselin' 'Parashkev Nachev' 'M. Jorge Cardoso'] Focal deficits in ischaemic stroke result from impaired perfusion downstream of a critical vascular occlusion. While parenchymal lesions are…
Authors not listed
Molecular mechanisms governing initiation steps of the assembly of thousands of endogenous multi-protein complexes (EMCs) remain incompletely understood. Here, multiple lines of observations are reported reflecting the biological functions-aligned initiation sequence of hybrid assembly pathways (HAPs) of EMCs. HAPs…