26 papers · ranked by Valyu relevance
R Dobrescu, VL Purcarea
The paper discusses the connection between emergence, pattern formation and nonlinear dynamics, focusing on the similarity between discrete patterns and fractal structures, and then describes different solutions to model reaction-diffusion systems as representative processes in morphogenesis. A specific example is the…
Jia Lu, Nan Luo, Sizhe Liu, Kinshuk Sahu + 3 more
Predictive programming of self-organized pattern formation using living cells is challenging in major part due to the difficulty in navigating through the high-dimensional design space effectively. The emergence and characteristics of patterns are highly sensitive to both system and environmental parameters. Often, the…
Authors not listed
This study investigates how the interaction between gene expression time delay and domain size governs spatio-temporal pattern formation in a reaction-diffusion system. To investigate these phenomena, we utilize a modified version of the Schnakenberg model called the ligand internalisation (LI) model. In a…
Jamie A. Davies, Fokion Glykofrydis
The development of natural tissues, organs and bodies depends on mechanisms of patterning and of morphogenesis, typically (but not invariably) in that order, and often several times at different final scales. Using synthetic biology to engineer patterning and morphogenesis will both enhance our basic understanding of…
Sabrina Meindlhumer, Jacob Kerssemakers, Cees Dekker
The Min protein system is arguably the best-studied model systems for biological pattern formation. It exhibits pole-to-pole oscillations in E. coli bacteria as well as a variety of surface wave patterns in in vitro reconstitutions. Such Min surface wave patterns pose particular challenges to quantification as they are…
Jan Rombouts, Jenna Elliott, Anna Erzberger
mechanochemical pattern formation Jan Rombouts et al Authors: ['Jan Rombouts' 'Jenna Elliott' 'Anna Erzberger'] Title: Abstract Biological pattern formation is essential for generating and maintaining spatial structures from the scale of a single cell to tissues and even collections of organisms. Besides biochemical…
Antonio Matas-Gil, Robert G. Endres
Controlling spatial patterns in synthetic biological systems remains challenging due to poor parameter robustness and limited experimental tunability. We introduce two complementary mechanisms—the pattern switch and the pattern dial—to systematically control Turing pattern formation in gene circuits. The switch toggles…
Kiryang Kwon, J. H. Choi
Spontaneous pattern formation out of homogeneous media is one of the well-understood examples of hydrodynamic instabilities in classical systems, which naturally leads to the question of its manifestation in quantum fluids. Bose-Einstein condensates (BECs) of atomic gases have been an ideal platform for studying…
Chengyou Yu, Malte Mederacke, Roman Vetter, Dagmar Iber
The evolution of multicellular organisms hinges on self-organization mechanisms that generate tissues with diverse functions. A central process is the breaking of symmetry to form spatial patterns from initially uniform conditions. Among the various mechanisms proposed, directed cell migration—driven by chemotaxis…
Laeschkir Würthner, Fridtjof Brauns, Grzegorz Pawlik, Jacob Halatek + 3 more
'Jacob Kerssemakers' 'Cees Dekker' 'Erwin Frey'] Self-organized pattern formation is vital for many biological processes. Reactiondiffusion models have advanced our understanding of how biological systems develop spatial structures, starting from homogeneity. However, biological processes inherently involve multiple…
Zezhong Xiang, Jin Li, Peng You, Linbo Han + 8 more
'Gengliang Chen' 'Yu He' 'Songqiang Liang' 'Boyuan Xiang' 'Yaorong Su' 'Hongyu An' 'Shunpu Li'] Regular patterns can form spontaneously in chemical reaction-diffusion systems under non-equilibrium conditions as proposed by Alan Turing. Here, we found that regular patterns can be generated in uphill-diffusion solution…
Sheng Wang, Jordi Garcia-Ojalvo, Michael B. Elowitz
Multicellular development employs periodic spatial patterning to generate repetitive structures such as digits, vertebrae, and teeth. Turing patterning has long provided a key paradigm for understanding such systems. The simplest Turing systems are believed to require at least two signals, or morphogens, that diffuse…
Frits Veerman, Moritz Mercker, Anna Marciniak-Czochra
Turing patterns are commonly understood as specific instabilities of a spatially homogeneous steady state, resulting from activator-inhibitor interaction destabilised by diffusion. We argue that this view is restrictive and its agreement with biological observations is problematic. We present two alternative to the…
Bakhtier Vasiev, Valentina Bucur
Biological pattern formation is one of the most intriguing phenomena in nature. Simplest examples of such patterns are represented by travelling waves and stationary periodic patterns which occur during various biological processes including morphogenesis and population dynamics. Formation of these patterns in…
Stephen Payne, Bochong Li, Yangxiaolu Cao, David Schaeffer + 2 more
'Marc D Ryser' 'Lingchong You'] Diverse mechanisms have been proposed to explain biological pattern formation. Regardless of their specific molecular interactions, the majority of these mechanisms require morphogen gradients as the spatial cue, which are either predefined or generated as a part of the patterning…
Nirmali Das, István Balázs, Bornali Das, Gergely Röst
This study investigates how the interaction between gene expression time delay and domain size governs spatio-temporal pattern formation in a reaction-diffusion system. To investigate these phenomena, we utilize a modified version of the Schnakenberg model called the LI (ligand internalisation) model. In a…
Vahid Nasirimarekani
droplet; formation of a flower-like pattern Authors: ['Vahid Nasirimarekani'] Pattern formation inside a liquid phase is a phenomenon involved in many different aspects of life on our planet. The droplet form of a liquid that evaporates can reveal patterns that depend on the chemistry of the droplet and the physical…
Murat Erkurt
The development of form in an embryo is the result of a series of topological and informational symmetry breakings. We introduce the vector-reaction-diffusion-drift (VRDD) system where the limit cycle of spatial dynamics is morphogen concentrations with Dirac delta-type distributions. This is fundamentally different…
Daniela Moreno, Yerko Ortiz, Diego Araya, Martín Gutiérrez
Voronoi diagrams are structures that have many applications. Parallel formation of Voronoi diagrams in cell colonies is a process that would enable to study a larger array of computational and biological problems using synthetic biology on cell colonies. In this study, we propose a spatial-resolution-based solution…
Noriaki Ogawa, Tetsuo Hatsuda, Atsushi Mochizuki, Masashi Tachikawa
A Markovian lattice model for photoreceptor cells is introduced to describe the growth of mosaic patterns on fish retina. The radial stripe pattern observed in wild-type zebrafish is shown to be selected naturally during the retina growth, against the geometrically equivalent, circular stripe pattern. The mechanism of…
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We report the discovery of highly ordered photoinduced patterns in two-dimensional layered copper halide perovskites under ultraviolet illumination in ultrahigh vacuum. In contrast to conventional random degradation observed in metal halide perovskites, these perovskites exhibit directional nanoscale grooves with…
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Laser modification of polymer surfaces is critical in many contexts including self-cleaning materials, microelectronics, and biomedical research. Despite their utility, accessing these modified polymers requires expensive or complex materials and multi-step fabrication, masking, and washing processes. Here, we present…
Neetu ., Aman Saini, Rishi Ram Mahato, Priyanka . + 1 more
The theory behind origin of life to Darwinian evolution considers emergence of dissipative structures driven by the flow of energy across all length scales. To this end, developing and deeper understanding of non-equilibrium self-assembly processes under continuous supply of energy is a demanding matter, both in…
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The capacity to pattern biomolecules within microfluidic devices expands the scope of microfluidic technologies. In such patterned systems, surface-bound components remained localized, while the microfluidic network supplies reagents and removes waste products. This approach has enabled continuous protein expression…
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Polymer-induced liquid precursors are hydrated, metastable, amorphous droplets rich in insoluble ionic compounds; they form in aqueous solutions that are supersaturated with mineral ions in the presence of charged polymers that delay the onset of crystal nucleation. This work reports that rapid crystallization of a…
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The discovery of quasicrystals, characterized by unique, non-repeating atomic arrangements and forbidden rotational symmetries, has significantly expanded our understanding of crystalline materials. However, controlling quasiperiodic length scales remains challenging because the quasiperiodic arrangements are often…