19 papers · ranked by Valyu relevance
Tarek Amer, Lila Davachi, Anna C Schapiro, Chris I Baker
Pattern separation, or the process by which highly similar stimuli or experiences in memory are represented by non-overlapping neural ensembles, has typically been ascribed to processes supported by the hippocampus. Converging evidence from a wide range of studies, however, suggests that pattern separation is a…
Harvey Wang, Selena Singh, Thomas Trappenberg, Abraham Nunes + 1 more
Pattern separation is a computational process by which dissimilar neural patterns are generated from similar input patterns. We present an information-geometric formulation of pattern separation, where a pattern separator is modeled as a family of statistical distributions on a manifold. Such a manifold maps an input…
Alexander D Bird, Hermann Cuntz, Peter Jedlicka
Pattern separation is a valuable computational function performed by neuronal circuits, such as the dentate gyrus, where dissimilarity between inputs is increased, reducing noise and increasing the storage capacity of downstream networks. A number of different measures (such as orthogonalisation, decorrelation, or…
Alexander D. Bird, Hermann Cuntz, Peter Jedlicka, Daniel Bush
Pattern separation is a valuable computational function performed by neuronal circuits, such as the dentate gyrus, where dissimilarity between inputs is increased, reducing noise and increasing the storage capacity of downstream networks. Pattern separation is studied from both in vivo experimental and computational…
Zhou, Dale, Noh, Sharon Mina + 10 more
The ability to discriminate similar visual stimuli has been used as an important index of memory function. This ability is widely thought to be supported by expanding the dimensionality of relevant neural codes, such that neural representations for the similar stimuli are maximally distinct, or "separated." An…
Sarang Saini, Rishikesh Narayanan
The Marr-Albus theory postulates that pattern separation is realized by divergent feedforward excitatory connectivity. Yet, there are several lines of evidence for strong but differential regulation of pattern separation by local circuit connectivity, even when feedforward connectivity is divergent. What are the…
Harvey Wang, Selena Singh, Thomas Trappenberg, Abraham Nunes
Evaluation of Existing Indices Authors: ['Harvey Wang' 'Selena Singh' 'Thomas Trappenberg' 'Abraham Nunes'] Pattern separation is a computational process by which dissimilar neural patterns are generated from similar input patterns. We present an information-geometric formulation of pattern separation, where a pattern…
La Grassa, Riccardo, Gallo, Ignazio + 2 more
Fine-grained classification models are designed to focus on the relevant details necessary to distinguish highly similar classes, particularly when intra-class variance is high and inter-class variance is low. Most existing models rely on part annotations—such as bounding boxes, part locations, or textual attributes—to…
Zsuzsanna Nemecz, István Homolya, Alex Ilyés, Hunor Kis + 4 more
Resolving interference between similar inputs is a critical feature of adaptive memory systems. Computational theories of the medial temporal lobe posit that the dentate gyrus and CA3 (CA3DG) subfields of the hippocampus are ideally suited to reduce interference via a process called pattern separation. Whereas…
Sang-Yoon Kim, Woochang Lim
Young immature granule cells (imGCs) appear via adult neurogenesis in the hippocampal dentate gyrus (DG). In comparison to mature GCs (mGCs) (born during development), the imGCs exhibit two competing distinct properties such as high excitability and low excitatory innervation. We develop a spiking neural network for…
Tarana Nigam, Caspar M. Schwiedrzik
Distinguishing faces requires well distinguishable neural activity patterns. Contextual information may separate neural representations, leading to enhanced identity recognition. Here, we investigate how predictions derived from contextual information affect the separability of neural activity patterns in the macaque…
Xin Ru, Ran Chen, Laihu Peng, Weimin Shi + 1 more
Patterns entered into knitting CAD have thousands or tens of thousands of different colors, which need to be merged by color-separation algorithms. However, for degraded patterns, the current color-separation algorithms cannot achieve the desired results, and the clustering quantity parameter needs to be managed…
Vahid Nasirimarekani
droplet; formation of a flower-like pattern Authors: ['Vahid Nasirimarekani'] Pattern formation inside a liquid phase is a phenomenon involved in many different aspects of life on our planet. The droplet form of a liquid that evaporates can reveal patterns that depend on the chemistry of the droplet and the physical…
Authors not listed
The formation and modulation of biomolecular condensates as well as their structural and dynamic properties are determined by an intricate interplay of different driving forces, which down at the microscopic scale involve molecular interactions of the biological macromolecules and the surrounding solvent and ions.…
Mélina Baheux Blin, Vincent Loreau, Frank Schnorrer, Pierre Mangeol
Regular spatial patterns are ubiquitous forms of organization in nature. In animals, regular patterns can be found from the cellular scale to the tissue scale, and from early stages of development to adulthood. To understand the formation of these patterns, how they form and mature, and how they are affected by…
Mélina Baheux Blin, Vincent Loreau, Frank Schnorrer, Pierre Mangeol
Regular spatial patterns are ubiquitous forms of organization in nature. In animals, regular patterns can be found from the cellular scale to the tissue scale, and from early stages of development to adulthood. To understand the formation of these patterns, how they assemble and mature, and how they are affected by…
Authors not listed
The capacity to pattern biomolecules within microfluidic devices expands the scope of microfluidic technologies. In such patterned systems, surface-bound components remained localized, while the microfluidic network supplies reagents and removes waste products. This approach has enabled continuous protein expression…
Neetu ., Aman Saini, Rishi Ram Mahato, Priyanka . + 1 more
The theory behind origin of life to Darwinian evolution considers emergence of dissipative structures driven by the flow of energy across all length scales. To this end, developing and deeper understanding of non-equilibrium self-assembly processes under continuous supply of energy is a demanding matter, both in…
Whitney Loo, Hongbo Feng, Beihang Yu, Scott Dhuey + 2 more
We report the use of a block copolymer (BCP) self-brushing mechanism for surface modification of Si substrates to heal defects in patterns generated for directed self-assembly (DSA). Our model system uses a lamellae-forming BCP consisting of a polystyrene block (PS) and a poly(glycidyl methacrylate) block (PG) that is…