13 papers · ranked by Valyu relevance
Jeffery M. Chakedis, Sharon B. Chang, Annie Tang, Gillian E. Kuehner + 3 more
'Alison C. Savitz' 'Brooke Vuong' 'Maihgan A. Kavanagh'] This cross-sectional study examines 5-year re-excision rates and use of recommended techniques among breast surgeons in a single health system.
Stacey Fisher, Yutaka Yasui, Kelly Dabbs, Marcy Winget
Background Increasing population-based evidence suggests that patients who receive breast conserving surgery (BCS) plus radiotherapy have superior survival than those who receive mastectomy. It is unclear, however, how BCS followed by re-excision is associated with all-cause and breast cancer-specific mortality, and…
Georgios Koulaxouzidis, Eugenia Schwarzkopf, Holger Bannasch, G. Björn Stark
'G. Björn Stark'] Background Soft tissue sarcomas (STS) are often diagnosed unexpectedly after surgery, and many excisions are incomplete. As histopathological assessments are challenging, patients later referred to comprehensive cancer centers (CCC) often come with an unclear status. This can make treatment planning…
Emmanuel Giannas, Konstantinos Kavallieros, Theodoros Nanidis, John Giannas + 3 more
Innovation in surgery and pelvic oncology have redefined the boundaries of pelvic exenteration for CRC. However, surgical approaches and outcomes following repeat exenteration and reconstruction are not well described. The resulting defect from a second beyond Total Mesorectal Excision (TME) presents a challenge to the…
Artūras Straižys, Michael Burke, Subramanian Ramamoorthy
— In surgery, the application of appropriate force levels is critical for the success and safety of a given procedure. While many studies are focused on measuring in situ forces, little attention has been devoted to relating these observed forces to surgical techniques. Answering questions like "Can certain changes to…
Qingyun Yang, Fangjie Li, Jiayi Xu, Zixuan Liu + 7 more
'Whitney Jin' 'Jennifer Du' 'Jon Heiselman' 'Michael Miga' 'Michael Topf' 'Jie Ying Wu'] Abstract. Head and neck squamous cell carcinoma (HNSCC) has one of the highest rates of recurrence cases among solid malignancies. Recurrence rates can be reduced by improving positive margins localization. Frozen section analysis…
Giovanni Buzzaccarini, Rebecca Susanna Degliuomini, Laura De Rosa, Silvia Villa + 4 more
'Silvia Villa' 'Silvia Messina' 'Gabriele Siesto' 'Massimo Candiani' 'Stefano Salvatore'] Title: Abstract The demand for female genital cosmetic surgery (FGCS) has significantly increased in recent years for two reasons: the advancement of surgical operations and the increased attention to women's esthetic and sexual…
Mustafa Zelal Muallem, Jalid Sehouli, Andrea Miranda, Helmut Plett + 6 more
Simple Summary When it comes to advanced vulval cancer management, there is a critical quandary to consider. This is owing to the severe negative impact of demolitive surgery on women who are afflicted by both functional and psychological consequences of the procedure. Primary closure of vulvar and/or perineal defects…
Yue Yang, Annie Benson, Matthieu Chabanas, Jason Slagle + 6 more
Positive margins in head and neck oncologic surgery require mapping specimen-side pathology findings to the patient resection bed. This is challenging because pathologists identify the positive margin on slices of the resected, deformed specimen, while surgeons must relocate the corresponding site on the resection bed…
Sylwia Machcinska, Marta Kopcewicz, Joanna Bukowska, Katarzyna Walendzik + 1 more
Hypoxia and hypoxia-regulated factors [hypoxia-inducible factor-1α (Hif-1α), factor inhibiting Hif-1α (Fih-1)] have essential roles in skin wound healing. Using Foxn1^-/-^ mice that can heal skin injuries in a unique scar-free manner, we investigated the interaction between Foxn1 and hypoxia-regulated factors.…
Emily C. Hank, Nicholas D'Arcy-Evans, Olov Wallner, Florian Ortis + 18 more
Emily C. Hank1,2 , Nicholas D'Arcy-Evans 1,2 , Emma Rose Scaletti 4 , Carlos Benítez-Buelga1,2,5 , Olov Wallner 1,2 , Florian Ortis1,2 , Kaixin Zhou 1 , Liuzhen Meng1,2 , Patricia Calvo 3 , Ingrid Almlöf 1 , Elisée Wiita1,2 , Sara Kosenina 4 , Andreas Krämer 9 , Maeve Long 1 , Ann-Sofie Jemth1,2 , Holly Dawson1,2 …
Jake Turley, Francesca Robertson, Isaac V. Chenchiah, Tanniemola B. Liverpool + 2 more
One of the key tissue movements driving closure of a wound is re-epithelialisation. Earlier wound healing studies have described the dynamic cell behaviours that contribute to wound re-epithelialisation, including cell division, cell shape changes and cell migration, as well as the signals that might regulate these…
Authors not listed
DNA is under constant attack by exogenous and endogenous agents that result in alkylation damage, which can lead to mutagenesis and cell death. 3-methyladenine DNA glycosylase II (AlkA) initiates the repair of many alkylated nucleotides in bacterial cells by cleaving the glycosidic bond connecting the damaged…