24 papers · ranked by Valyu relevance
Krishna Prasad Acharya, Santosh Pathak
Research and development (R&D) offer promising clues to address a wide range of socioeconomic problems through the development of new products and services or often by improving the existing ones. High-income countries (HICs) have realized the worth of R&D and invested tremendously in that sector; however…
Kow Ansah-Mensah, Adams Osman, Clarke Ebow Yalley, Kofi Adu-Boahen + 1 more
'Asst. Prof. Dr. Nemer Badwan'] In a time of severe environmental problems and growing public and private expenditure to promote a sustainable society, studies on the impact of Research and Development (R&D) on environmental sustainability hardly ever exist. This study looked at how R&D promotes the attainment of…
Ahmad Salman, Saja A. Fakhraldeen, Sungsoo Chun, Kazi Jamil + 2 more
'Janvier Gasana' 'Adel Al-Hunayan'] Kuwait Vision 2035 is an initiative that was launched in 2017 by His Highness the Emir of the State of Kuwait Sheikh Sabah Al-Ahmad Al-Jaber Al-Sabah. This initiative includes the implementation of a detailed development plan aimed at transforming the state of Kuwait into a regional…
Krishna Prasad Acharya, Santosh Pathak
In the second paragraph of the Introduction of the original article, there was an incomplete sentence with a missing citation and overlapping text stating that “Although resources must be allocated in advance to R&D, the innovations gained through the research can actually work to reduce costs through more efficient…
Rampalli Viswa Chandra, Devaraju Rama Raju
The study had two aims. 1) Analysis of research projects done in our institution from 2014-2019 to identify products with a potential for commercialization and 2) To understand the effect of product-development variables on research projects to improve the quality of future commercialization-oriented trials. 338…
Christopher Southan
This report covers academic small-molecule drug development with a view to distilling guidelines. The first section covers research productivity feeding into commercial development before reviewing the literature on statistics of academic development It then considers differences between probes and drugs before…
Anthony J. Culyer, Kalipso Chalkidou
Research and Development (R&D) in health and health care has several intriguing characteristics which, separately and in combination, have significant implications for the ways in which it is organised, funded and managed. We review the characteristics, some of which apply under most circumstances and others of which…
Fernando Almeida, Nelson Amoedo
Investment in research and development is a key factor in increasing countries' competitiveness. However, its impact can potentially be broader and include other socially relevant elements like job quality. In effect, the quantity of generated jobs is an incomplete indicator since it does not allow to conclude on the…
Lem Ngongalah, Ngwa Niba Rawlings, Emerson Wepngong, James Musisi + 2 more
Improved capacity for research is a valuable and sustainable means of advancing health and development in Africa. Local leadership in research capacity strengthening is important for developing contextually appropriate programs that increase locally-driven research, and improve Africa’s ability to adapt and use…
Michael D. Schaller
Federal funding for research has immediate and long-term economic impact. Since federal research funding is regionally concentrated and not geographically distributed, the benefits are not fully realized in some regions of the country. The Established (previously Experimental) Program to Stimulate Competitive Research…
Christopher Southan
This report covers academic small-molecule drug development with a view to distilling guidelines. The first section covers research productivity feeding into commercial development before reviewing the literature on statistics of academic development It then considers differences between probes and drugs before…
Shiro Takagi
This paper engages in a speculative exploration of the concept of an artificial agent capable of conducting research. Initially, it examines how the act of research can be conceptually characterized, aiming to provide a starting point for discussions about what it means to create such agents. The focus then shifts to…
Nasir U. Eisty, Jeffrey C. Carver
Background: Research software plays an important role in solving real-life problems, empowering scientific innovations, and handling emergency situations. Therefore, the correctness and trustworthiness of research software are of absolute importance. Software testing is an important activity for identifying problematic…
А. В. Палагин, Vitalii Velychko, Kyrylo Malakhov, Олександр Щуров
Against the backdrop of the development of modern technologies in the field of scientific research, the new class of Current Research Information Systems (CRIS) and related intelligent information technologies have arisen. It was called – Research and Development Workstation Environment (RDWE) – the comprehensive…
Rajkumar Buyya, Sukhpal Singh Gill, Satish Narayana Srirama, Rami Bahsoon + 1 more
'Rami Bahsoon' 'San Murugesan'] 2 School of Electronic Engineering and Computer Science, Queen Mary University of London, UK 3 School of Computer and Information Sciences, University of Hyderabad, India. 4 Mobile & Cloud Lab, Institute of Computer Science, University of Tartu, Estonia 5 School of Computer Science…
Sarah M. Farris
Purely discovery-driven biological research “…performed without thought of practical ends…” establishes fundamental conceptual frameworks for technological and medical breakthroughs that often occur many years later. Despite the critical importance of discovery-driven research for scientific progress, there is…
Junghun Chae, WooJoong Kim, Woochul Jung, Dawoon Jeong + 17 more
Current technological revolutions, involving artificial intelligence, mRNA vaccines, and quantum computing, are largely driven by industry. Despite the existing perception that commercial motives promote cutting-edge innovation, concerns may arise about their risk of limiting scientific exploration from diverse…
Matt Clancy
This paper develops a novel estimates of annual private sector agricultural R&D at the level of US states for the period 1976-2014. For each of five different agricultural subsectors, I allocate estimates of national private sector R&D across the 50 states by using the geographic distribution of inventors listed on…
Hossein Hassani
Research methods are essential parts in conducting any research project. Although they have been theorized and summarized based on best practices, every field of science requires an adaptation of the overall approaches to perform research activities. In addition, any specific research needs a particular adjustment to…
Yunfang Chen, Qingkui Lai, Xuan Ji, Cunyu zhang + 1 more
Green development is important to realize the coordinated development of local ecological environment, economy and society, but also an important way to promote the harmony between human and land. This study utilizes projection pursuit model (PPM) measure, as well as the system gray prediction model GM (1, N), and…
Rumiana Tenchov, Janet Sasso, Xinmei Wang, Qiongqiong Angela Zhou
Aging is a dynamic, time-dependent process characterized by a gradual accumulation of cell damage. Continual functional decline in the intrinsic ability of living organisms to accurately regulate homeostasis leads to increased susceptibility and vulnerability to diseases. Anti-aging research has a long history…
David Snead, Yonghong Gan, Thomas Scattolin, Dinesh Paymode + 11 more
A commercial route to MRTX849 (adagrasib) was developed to support clinical and commercial needs. Yield was improved to 32% over six chemical steps. A doubly regioselective SNAr reduced consumption of an expensive chiral intermediate, reaction optimization led to parts per million palladium catalysis, and a new method…
Sharon Pinus, Jérôme Genzling, Mihai Burai-Patrascu, Nicolas Moitessier
Computational asymmetric catalysis has seen an impressive rise in the last twenty years, thanks to advancements in algorithm and method development for predicting catalyst enantioselectivity. These methods/algorithms describe reactions that can be categorized into two groups: reactions where 1) knowledge of the…
Tesfay Tesfatsion, Arianna Collins, Giovanni Ramirez, Yousef Mzannar + 6 more
Cannabinoid receptors CB1 and CB2 are the primary endogenous receptors with which cannabinoids interact, inducing physiological and psychological effects. Although interactions with other receptors including TRPV1 and GPCR55, have been recognized in earlier studies, these interactions may play a significant role in…