21 papers · ranked by Valyu relevance
Tom Boissonnet, Matteo Tripodi, Hiroki Asari, Fred Rieke + 1 more
'Andrew J King'] The structure and function of the vertebrate retina have been extensively studied across species with an isolated, ex vivo preparation. Retinal function in vivo, however, remains elusive, especially in awake animals. Here, we performed single-unit extracellular recordings in the optic tract of…
Na Young Jun, Greg D. Field, John M. Pearson
Among the most striking features of retinal organization is the grouping of its output neurons, the retinal ganglion cells (RGCs), into a diversity of functional types. Each of these types exhibits a mosaic-like organization of receptive fields (RFs) that tiles the retina and visual space. Previous work has shown that…
Khaled Masmoudi, Marc Antonini, Pierre Kornprobst
We propose the design of an original scalable image coder/decoder that is inspired from the mammalians retina. Our coder accounts for the time-dependent and also nondeterministic behavior of the actual retina. The present work brings two main contributions: As a first step, (i) we design a deterministic image coder…
Ulisse Ferrari, Christophe Gardella, Olivier Marre, Thierry Mora
According to the theory of efficient coding, sensory systems are adapted to represent natural scenes with high fidelity and at minimal metabolic cost. Testing this hypothesis for sensory structures performing non-linear computations on high dimensional stimuli is still an open challenge. Here we develop a method to…
Samuel A. Ocko, Jack Lindsey, Surya Ganguli, Stephane Deny
One of the most striking aspects of early visual processing in the retina is the immediate parcellation of visual information into multiple parallel pathways, formed by different retinal ganglion cell types each tiling the entire visual field. Existing theories of efficient coding have been unable to account for the…
Divyansh Gupta, Wiktor Młynarski, Anton Sumser, Olga Symonova + 2 more
Statistics of natural scenes are not uniform - their structure varies dramatically from ground to sky. It remains unknown whether these non-uniformities are reflected in the large-scale organization of the early visual system and what benefits such adaptations would confer. Here, by relying on the efficient coding…
Kyle Bojanek, Olivier Marre, Stephanie E. Palmer
Populations of sensory neurons are thought to be shaped by selective pressures for optimal information transmission, yet real neural circuits display substantial variability across stimulus repeats, across time, and between individuals. Reconciling this variability with normative theories requires understanding not…
Ulisse Ferrari, Christophe Gardella, Olivier Marre, Thierry Mora
According to the theory of efficient coding, sensory systems are adapted to represent natural scenes with high fidelity and at minimal metabolic cost. Testing this hypothesis for sensory structures performing non-linear computations on high dimensional stimuli is still an open challenge. Here we develop a method to…
Camilo Miguel Signorelli
This exploratory project report provides a study of the retina in response to spontaneous and evoked pattern of flashes for different time cycles. These patterns induce changes at individual neural level and network level, while global efficiency, a topological network measure, presents robustness and degenerate states…
Dimokratis Karamanlis, Mohammad H. Khani, Helene M. Schreyer, Sören J. Zapp + 2 more
'Sören J. Zapp' 'Matthias Mietsch' 'Tim Gollisch'] The role of the vertebrate retina in early vision is generally described by the efficient coding hypothesis1,2, which predicts that the retina reduces the redundancy inherent in natural scenes3 by discarding spatiotemporal correlations while preserving stimulus…
Bingao Zhang, Rong Zhang, Jingjin Zhao, Jiarui Yang + 1 more
Vision plays a major role in perceiving external stimuli and information in our daily lives. The neural mechanism of color vision is complicated, involving the co-ordinated functions of a variety of cells, such as retinal cells and lateral geniculate nucleus cells, as well as multiple levels of the visual cortex. In…
Ru-Jia Yan, Hai-Qing Gong, Pu-Ming Zhang, Pei-Ji Liang
How visual information is encoded in spikes of retinal ganglion cells (RGCs) is essential in visual neuroscience. In the present study, we investigated the coding properties of mouse RGCs with dual-peak patterns with respect to visual stimulus intervals. We first analyzed the response properties, and observed that the…
Markus Meister
The scientific study of the retina has reached a remarkable state of completion. We can now explain many aspects of early visual processing based on a relatively simple model of neural circuitry in the retina. The same model, with different parameters, produces a great diversity of neural computations. In this article…
Jessica Rodgers, Steven Hughes, Moritz Lindner, Annette E Allen + 5 more
Photoreceptor degeneration sufficient to produce severe visual loss often spares the inner retina. This raises the hope that treatments using optogenetics or electrical stimulation, which generate a replacement light input signal in surviving neurons, may restore vision. The success of these approaches is dependent on…
Zhaofei Yu, Jian K. Liu, Shanshan Jia, Yichen Zhang + 3 more
'Yonghong Tian' 'Tiejun Huang'] Neuroprosthesis, as one type of precision medicine device, is aiming for manipulating neuronal signals of the brain in a closed-loop fashion, together with receiving stimulus from the environment and controlling some part of our brain/body. In terms of vision, incoming information can be…
Ernest Greene
There is perceptual and physiological evidence that the retina registers and signals luminance and luminance contrast using dual-channel mechanisms. This process begins in the retina, wherein the luminance of a uniform zone and differentials of luminance in neighboring zones determine the degree of brightness or…
Kristof Van Schil, Marcus Karlstetter, Alexander Aslanidis, Katharina Dannhausen + 6 more
'Katharina Dannhausen' 'Maleeha Azam' 'Raheel Qamar' 'Bart P. Leroy' 'Fanny Depasse' 'Thomas Langmann' 'Elfride De Baere'] The aim of this study was to unravel the molecular pathogenesis of an unusual retinitis pigmentosa (RP) phenotype observed in a Turkish consanguineous family. Homozygosity mapping revealed two…
Shinyong Shim, Kyungsik Eom, Joonsoo Jeong, Sung June Kim
Retinal prostheses are implantable devices that aim to restore the vision of blind patients suffering from retinal degeneration, mainly by artificially stimulating the remaining retinal neurons. Some retinal prostheses have successfully reached the stage of clinical trials; however, these devices can only restore…
Aman Chawla
In this brief paper, the authors study the tuning curves of starburst amacrine cells (SACs) and introduce a quantity called the irresolution or ambiguity of a SAC. They show that the rate of data generated by a starburst amacrine cell is inversely proportional to its irresolution. This is done by providing bounds on…
Konstantin Komarov, Woojin Park, Seunghoon Lee, Miquel Huix-Rotllant + 1 more
It is demonstrated that significant accuracy improvements of MRSF-TDDFT can be achieved by introducing two different XC functionals for the reference Kohn-Sham DFT and the response part of calculations, respectively. Accordingly, two new exchange-correlation (XC) functionals of DTCAM-VEE and DTCAM-AEE were developed on…
Authors not listed
Channelrhodopsin-2 (ChR2) is a light-gated ion channel widely used in optogenetics, a technique that enables precise control of neuronal activity by genetically engineering light-sensitive proteins into cell membranes. This protein exists in dimeric form, with each monomer containing a retinal Schiff base (RSB) moiety…