23 papers · ranked by Valyu relevance
Dinis Gökaydin, Peter Brugger, Tobias Loetscher
Small and large numbers are typically associated with the left and right side of space, respectively. We conducted an online version of the classical Spatial-Numerical Association of Response Codes (SNARC) paradigm in 604 subjects in order to analyse how previous trials and responses affect SNARC. Our results point to…
Daniel P. Wickland, Yingxue Ren, Jason P. Sinnwell, Joseph S. Reddy + 12 more
'Cyril Pottier' 'Vivekananda Sarangi' 'Minerva M. Carrasquillo' 'Owen A. Ross' 'Steven G. Younkin' 'Nilüfer Ertekin-Taner' 'Rosa Rademakers' 'Matthew E. Hudson' 'Liudmila Sergeevna Mainzer' 'Joanna M. Biernacka' 'Yan W. Asmann' 'Alvaro Galli'] Genetic studies have shifted to sequencing-based rare variants discovery…
Jennifer A. Tom, Jens Reeder, William F. Forrest, Robert R. Graham + 3 more
'Julie Hunkapiller' 'Timothy W. Behrens' 'Tushar R. Bhangale'] Background Large sample sets of whole genome sequencing with deep coverage are being generated, however assembling datasets from different sources inevitably introduces batch effects. These batch effects are not well understood and can be due to changes in…
Song-Ze Yu, Milan Liessens Dujardin, Yuxuan Cai, Wantong Zhang
We present InstructFX2FX, an interactive demonstration of multi-turn, text-guided audio effect refinement. Existing text-to-preset systems are largely single-shot, mapping one textual descriptor to one preset. Real audio engineering is instead sequential: engineers refine an existing effect chain through successive…
Liang Zhao, Yonghui Wang, Amanda Bruce
Congruency sequence effects refer to the reduction of congruency effects when following an incongruent trial than following a congruent trial. The conflict monitoring account, one of the most influential contributions to this effect, assumes that the sequential modulations are evoked by response conflict. The present…
Rina Friedberg, R. G. Mudd, Patrick R. Johnstone, Melissa Pothen + 3 more
Sequential treatment assignments in online experiments lead to complex dependency structures, often rendering identification, estimation and inference over treatments a challenge [[Kohavi et al., 2012]]. Treatments in one session (e.g., a user logging on) can have an effect that persists into subsequent sessions…
Yuan-Chiao Cheng, Jui-Te Wu, Brian Chen, Yen-Tung Yeh + 2 more
Audio mixing style encompasses the artistic and technical decisions a mix engineer makes, including level balancing, spatialization, and the choice, ordering, and parameterization of audio effects (FX) on each stem. FX chains are a key determinant of this style, yet existing approaches to modeling them remain limited.…
Qiangqiang Wang, Mowei Liu, Wendian Shi, Jingmei Kang
The spatial-numerical association of response codes (SNARC) effect refers to the phenomenon that responses involving small numbers are faster with the left hand and responses involving large numbers are faster with the right hand. Previous studies have investigated the mechanism of the SNARC effect only when the time…
Samuel Planton, Timo van Kerkoerle, Leïla Abbih, Maxime Maheu + 7 more
'Florent Meyniel' 'Mariano Sigman' 'Liping Wang' 'Santiago Figueira' 'Sergio Romano' 'Stanislas Dehaene' 'Blake A. Richards'] Working memory capacity can be improved by recoding the memorized information in a condensed form. Here, we tested the theory that human adults encode binary sequences of stimuli in memory using…
Authors not listed
Sequence is the critical determinant of macromolecular function, yet current polymer design approaches often optimize monomer composition and ratios while ignoring sequence. This creates poorly defined design spaces for active learning that miss the vast combinatorial landscape of sequence possibilities. We introduce…
Ivana Djurišić, Miloš S. Dražić, Aleksandar Ž. Tomović, Marko Spasenović + 2 more
'Marko Spasenović' 'Vladimir P. Jovanović' 'Radomir Žikić'] Fast, reliable and inexpensive DNA sequencing is an important pursuit in healthcare, especially in personalized medicine with possible deep societal impacts. Despite significant progress of various nanopore-based sequencing configurations, challenges remain in…
Stacey Anne Gould, Amy Hodgson, Hannah F. Clarke, Trevor W. Robbins + 1 more
Self-ordered sequencing is an important executive function involving planning and executing a series of steps to achieve goal-directed outcomes. Lateral frontal cortex is implicated in this behavior, but downstream striatal outputs remain relatively unexplored. We trained marmosets on a three-stimulus self-ordered…
Hesaam Esfandyarpour, Kosar B. Parizi, Meysam R. Barmi, Hamid Rategh + 58 more
High throughput DNA sequencing technologies have undergone tremendous development over the past decade. Although optical detection-based sequencing has constituted the majority of data output, it requires a large capital investment and aggregation of samples to achieve optimal cost per sample. We have developed a novel…
Kevin Zhang, Neha Patki, Kalyan Veeramachaneni
The goal of this paper is to describe a system for generating synthetic sequential data within the Synthetic data vault. To achieve this, we present the Sequential model currently in SDV, an end-to-end framework that builds a generative model for multi-sequence, real-world data. This includes a novel neural…
Michael Bale, Malamati Bitzidou, Anna Pitas, Leonie Brebner + 4 more
The world around us is replete with stimuli that unfold over time. When we hear an auditory stream like music or speech or scan a texture with our fingertip, physical features in the stimulus are concatenated in a particular order, and this temporal patterning is critical to interpreting the stimulus. To explore the…
Authors not listed
Large-scale de novo nucleic acid synthesis is a powerful tool enabling researchers to better understand and engineer biological systems. Fields ranging from genomics to nucleic acid therapeutics to synthetic biology make use of high-throughput experimental approaches requiring access to large pools or libraries of DNA…
Nicholas Boyd, Samuel Woodhouse, Kalim U. Mir
Sequencing by Emergence (SEQE) is a new single-molecule nucleic acid (DNA/RNA) sequencing technology that estimates sequence as an emergent property of the binding and localization of a repertoire of short oligonucleotide probes. SEQE promises to deliver accurate, ultra-long, haplotype-phased reads at the whole…
Yipeng Yin, Reed Arneson, Yinan Yuan, Shiyue Fang
The longest oligos that can be chemically synthesized using known methods are typically considered to be 200-mers. Here, we report direct synthesis of an 800-mer green fluorescent protein (GFP) gene and a 1,728-mer Φ29 DNA polymerase gene on an automated synthesizer. Key innovations that enabled the breakthrough…
Matthew A. Petroff
—Color sequences, ordered sets of colors for data visualization, that balance aesthetics with accessibility considerations are presented. In order to model aesthetic preference, data were collected with an online survey, and the results were used to train a machine-learning model. To ensure accessibility, this model…
Wout Bittremieux, Varun Ananth, William E. Fondrie, Carlo Melendez + 5 more
Protein tandem mass spectrometry data is most often interpreted by matching observed mass spectra to a protein database derived from the reference genome of the sample being analyzed. In many application domains, however, a relevant protein database is unavailable or incomplete, and in such settings de novo sequencing…
Ratanond Koonchanok, Swapna Vidhur Daulatabad, Quoseena Mir, Khairi Reda + 1 more
Sequoia is a visualization tool that allows biologists to explore characteristics of signals generated by the Oxford Nanopore Technologies (ONT) in detail. From Fast5 files generated by ONT, the tool displays relative similarities between signals using the dynamic time warping and the t-SNE algorithms. Raw signals can…
Ariya Shajii, Ibrahim Numanagić, Alexander T. Leighton, Haley Greenyer + 2 more
Exponentially-growing next-generation sequencing data requires high-performance tools and algorithms. Nevertheless, the implementation of high-performance computational genomics software is inaccessible to many scientists because it requires extensive knowledge of low-level software optimization techniques, forcing…
Michael Lanzillotti, Jennifer Brodbelt
Recent progress in top-down mass spectrometry analysis of progressively larger nucleic acids has enabled in-depth characterization of intact, modified RNA molecules. Development of methods for desalting and MS/MS fragmentation allows rapid acquisition of high-quality top-down MS/MS spectra of nucleic acids up to 100…