23 papers · ranked by Valyu relevance
Arthur P Arnold
From the moment of our conception, each of us has a sex. Sex has a major role in determining the physical attributes of our bodies, the structure of our brains, our behavioral tendencies, our susceptibility and reaction to diseases, the environment in which we grow up, our place in society, the attitudes of others…
Muataz S. Lafta, Jessica Mwinyi, Oreste Affatato, Gull Rukh + 3 more
'Junhua Dang' 'Gerhard Andersson' 'Helgi B. Schiöth'] Increased knowledge about sex differences is important for development of individualized treatments against many diseases as well as understanding behavioral and pathological differences. This review summarizes sex chromosome effects on gene expression, epigenetics…
Geert J. de Vries, Nancy G. Forger
Most writing on sexual differentiation of the mammalian brain (including our own) considers just two organs: the gonads and the brain. This perspective, which leaves out all other body parts, misleads us in several ways. First, there is accumulating evidence that all organs are sexually differentiated, and that sex…
K. S. Burrowes, M. Ruppage, A. Lowry, D. Zhao
Personalised medicine and the development of a virtual human or a digital twin comprises visions of the future of medicine. To realise these innovations, an understanding of the biology and physiology of all people are required if we wish to apply these technologies at a population level. Sex differences in health and…
Jiamin Ma, Lishi Wang, Gang Yuan, Chrishan Fernando + 12 more
Males and females possess genomes that are almost identical but differ in morbidity, prevalence, severity, response to therapies and mortality of many diseases. We comprehensively analyzed gene expression data in seven tissues from BXD recombinant inbred (RI) mouse strains. We found that there were considerable…
Aura Zelco, Pattama Wapeesittipan, Anagha Joshi, Qian Du
The societal implication of sex and gender (SG) differences in brain are profound, as they influence brain development, behavior, and importantly, the presentation, prevalence, and therapeutic response to diseases. Technological advances have enabled speed up identification and characterization of SG differences during…
Gonzalo R. Quintana, James G. Pfaus
The largely binary nature of biological sex and its conflation with the socially constructed concept of gender has created much strife in the last few years. The notion of gender identity and its differences and similarities with sex have fostered much scientific and legal confusion and disagreement. Settling the…
Cho-Yi Chen, Camila Lopes-Ramos, Marieke L. Kuijjer, Joseph N. Paulson + 6 more
Sexual dimorphism manifests in many diseases and may drive sex-specific therapeutic responses. To understand the molecular basis of sexual dimorphism, we conducted a comprehensive assessment of gene expression and regulatory network modeling in 31 tissues using 8716 human transcriptomes from GTEx. We observed sexually…
Lily R. Qiu, Darren J. Fernandes, Kamila U. Szulc, Jun Dazai + 4 more
Sex differences exist in behaviours, disease and neuropsychiatric disorders. Sexual dimorphisms however, have yet to be studied across the whole brain and across a comprehensive time course of postnatal development. We used manganese-enhanced MRI (MEMRI) to longitudinally image male and female C57BL/6J mice across 9…
Charlotte A Veser, Aurélie Carlier, Silvia M. Mihăilă, Sangita Swapnasrita
'Sangita Swapnasrita'] In vitro models play a crucial role in advancing our understanding of biological processes, disease mechanisms, and developing screening platforms for drug discovery. Kidneys play an instrumental role in transport and elimination of drugs and toxins. However, despite the wellestablished…
Yumnah T. Khan, Alex Tsompanidis, Marcin A. Radecki, Lena Dorfschmidt + 6 more
Sex differences in human brain anatomy have been well-documented; however, their underlying causes remain controversial. Neonatal research offers a pivotal opportunity to address this long-standing debate. Given that postnatal environmental influences (e.g., gender socialisation) are minimal at birth, any sex…
Carinna Torgerson, Kathserine Bottenhorn, Hedyeh Ahmadi, Jeiran Choupan + 1 more
Adolescent neuroimaging studies of sex differences in the human brain predominantly examine mean differences between males and females. This focus on between-groups differences without probing relative distributions and similarities may contribute to both conflation and overestimation of sex differences and sexual…
Shuo Zhou, Junhao Luo, Yaya Jiang, Haolin Wang + 2 more
differences in lateralization of brain functional network Authors: ['Shuo Zhou' 'Junhao Luo' 'Yaya Jiang' 'Haolin Wang' 'Haiping Lu' 'Gaolang Gong'] Lateralization is a fundamental feature of the human brain, where sex differences have been observed. Conventional studies in neuroscience on sex-specific lateralization…
Haluk O. Bingol, Omer Basar
Until very recently we all live in a physical world only. With the rapid penetration of Internet to our daily lives starting in mid 1990's, we developed a new concept of virtual world. Now we have virtual friends that we exchange emails or tweets. We used to live in our social network, which was within our physical…
Klaus Jaffé, Guillermo Mascitti, Daniella Seguias
Results: Duration of sounds lasting less than 10 s were on average overestimated, whereas those lasting longer were underestimated; estimates of sounds shorter than 1 s were extremely inaccurate. Females consistently gave longer estimates than males. Accuracy in time estimation was correlated to academic performance in…
Mila Bertolo, Daniel Müllensiefen, Isabelle Peretz, Sarah C. Woolley + 2 more
Since Darwin^1^, researchers have proposed that human musicality evolved in a reproductive context in which males produce music to signal their mate quality to females. Sexually selected traits involve tradeoffs in the costs of high-quality signal production and high-fidelity signal detection^2^, leading to observable…
Giovanni Abramo, Ciriaco Andrea D’Angelo, Alessandro Caprasecca
The state of the art on the issue of sex differences in research efficiency agrees in recognizing higher performances for males, however there are divergences in explaining the possible causes. One of the causes advanced is that there are sex differences in the availability of aptitude at the "high end". By comparing…
N.E. Farias, P. Ribeiro, J.P. Lancia, T. Luppi
Explanations for the evolution of male-biased size dimorphism (MBSSD) traditionally focus on male competition and female choice, overlooking the alternative that larger males may be better at coercing females into mating. While displaying considerable diversity, ‘true crabs’ (Eubrachyura) share common traits that…
Mike Thelwall, Emma Stuart
Information about gender differences in interests is necessary to disentangle the effects of discrimination and choice when gender inequalities occur, such as in employment. This article assesses gender differences in interests within the popular social news and entertainment site Reddit. A method to detect terms that…
Kassandra Friedrichs, Philipp Kellmeyer
Over the last three decades, the human brain, and its role in determining behavior have been receiving a growing amount of attention in academia as well as in society more generally. Neuroscientific explanations of human behavior or other phenomena are often especially appealing to lay people. Therefore…
Authors not listed
Introduction: Blood microsampling (BµS) devices collect less than 100 µL of blood, offering a less invasive and more cost-effective alternative to venipuncture. However, its metabolomic comparability to conventional samples remains unclear, and standardized BµS metabolomic workflows are lacking. Objectives: This study…
Ashraf El-Sayed, Lee-Anne Manning
The pink grass worm, Tmetolophota atristriga (Walker), is a New Zealand native species. It is abundant throughout the North and South Islands and is a pest which defoliates pasture. In this study, the sex pheromone of this species was investigated. Analysis of the extract of the female sex pheromone gland by GC/EAD…
Jiwon Lee
Dopamine is a hormone that is released by the adrenal gland and influences motor control and motivation. Dopamine is known to have 5 receptors which are D1, D2, D3, D4 and D5, which are further categorized into 2 families: D1 family and D2 family. The D1 family is known to play a role in motivation and motor control…