26 papers · ranked by Valyu relevance
Tim P. Morris, Ian R. White, Michael J. Crowther
Simulation studies are computer experiments that involve creating data by pseudorandom sampling. A key strength of simulation studies is the ability to understand the behaviour of statistical methods because some 'truth' (usually some parameter/s of interest) is known from the process of generating the data. This…
Guillaume Lamé, Mary Dixon-Woods
Simulation can offer researchers access to events that can otherwise not be directly observed, and in a safe and controlled environment. How to use simulation for the study of how to improve the quality and safety of healthcare remains underexplored, however. We offer an overview of simulation-based research (SBR) in…
Hugh Chipman, Derek Bingham
Statisticians recommend the Design and Analysis of Experiments (DAE) for evidence-based research but often use tables to present their own simulation studies. Could DAE do better? We outline how DAE methods can be used to plan and analyze simulation studies. Tools for planning include fishbone diagrams, factorial and…
Kim Luijken, Adolf W. Lohmann, Udi Alter, J. Claramunt Gonzalez + 12 more
'Felix J. Clouth' 'Jessica Fossum' 'L. Hesen' 'A. H. J. Huizing' 'J. Α. Α. Ketelaar' 'Amanda Kay Montoya' 'Linda Nab' 'R. C. C. Nijman' 'Bas B. L. Penning de Vries' 'Tristan Tibbe' 'Alex Wang' 'Rolf H. H. Groenwold'] Results of simulation studies evaluating the performance of statistical methods are often considered…
Breno Bernard Nicolau de França, Dietmar Pfahl, Valdemar Vicente Graciano Neto, Nauman bin Ali
Engineering Authors: ['Breno Bernard Nicolau de França' 'Dietmar Pfahl' 'Valdemar Vicente Graciano Neto' 'Nauman bin Ali'] Abstract The chapter supports educators and postgraduate students in understanding the role of simulation in software engineering research based on the authors' experience. This way, it includes a…
Samuel Pawel, Lucas Kook, Kelly Reeve
Comparative simulation studies are workhorse tools for benchmarking statistical methods. As with other empirical studies, the success of simulation studies hinges on the quality of their design, execution and reporting. If not conducted carefully and transparently, their conclusions may be misleading. In this paper we…
Samuel Pawel, František Bartoš, Björn S. Siepe, Anna Lohmann
Studies: A Review of Current Practices and Recommendations Authors: ['Samuel Pawel' 'František Bartoš' 'Björn S. Siepe' 'Anna Lohmann'] Simulation studies are commonly used in methodological research for the empirical evaluation of data analysis methods. They generate artificial data sets under specified mechanisms and…
Corrine F. Elliott, James Duncan, Tiffany Tang, Merle Behr + 2 more
'Karl Kumbier' 'Bin Yu'] Simulations play a crucial role in the modern scientific process. Yet despite (or due to) their ubiquity, the Data Science community shares neither a comprehensive definition for a "high-quality" study nor a consolidated guide to designing one. Inspired by the…
Niall McInerney, D. Nally, M.F. Khan, H. Heneghan + 1 more
Objective: Simulation based medical education (SBME) is fast becoming embedded into undergraduate medical curricula with many publications now describing its various modes and student self-reported impacts. This systematic review synthesizes the available literature for evidence of performance effects of SBME as an…
Minh Chau, Elio Arruzza, Nathan Johnson
Simulation-based education is a significant aspect of teaching clinical skills in tertiary medical radiation science programmes, allowing students to experience the clinical setting in a safe environment. As an educational tool, simulation exists in many valid forms including role play, interprofessional simulation and…
Ignacio Manuel Guerrero-Martínez, Francisco Javier Portero-Prados, Rocío Cándida Romero-González, Rocío Romero-Castillo + 2 more
'Rocío Cándida Romero-González' 'Rocío Romero-Castillo' 'Manuel Pabón-Carrasco' 'José Antonio Ponce-Blandón'] (1) Background: Simulation is a part of the day-to-day of the learning method in health sciences. The objective is to determine if the clinical simulation is useful for learning in the emergency setting, from…
Joshua Epuitai, Pamella R. Adongo, Paul Oboth, Felister Apili + 3 more
This was a qualitative study which used a grounded theory approach to understand stake-holders experiences and perceptions of simulation in our setting. We used qualitative methods to collect the data for the study. The study was conducted in Busitema University Faculty of Health Sciences (BUFHS) and Lira University…
Camilla Olaussen, Kristin Heggdal, Christine Raaen Tvedt
1## INTRODUCTION Scenario-based simulation using a computerized full-body-size patient simulator facilitates the mimicry of real-life situations (Cato, [nop2375-bib-0008]; Hicks, Coke, & Li, [nop2375-bib-0017]; Shin, Jin-Hva, & Jung-Hee, [nop2375-bib-0036]). The use of such simulators may enhance fidelity for many…
Alette H. Svellingen, Margrethe B. Søvik, Kari Røykenes, Guttorm Brattebø
The time frame over which the studies were conducted varied between two weeks, several semesters and years. Simulation sessions were related to different medical courses, including paediatric, medical-surgical, mental health, critical care, acute patient deterioration and adult nursing courses. Additionally, one study…
Jori Liesenborgs, Diana M Hendrickx, Elise Kuylen, David Niyukuri + 2 more
SimpactCyan is an open-source simulator for individual-based models in HIV epidemiology. Its core algorithm is written in C++ for computational efficiency, while the R and Python interfaces aim to make the tool accessible to the fast-growing community of R and Python users. Transmission, treatment and prevention of HIV…
Janine Egert, Clemens Kreutz
In systems biology, the analysis of complex nonlinear systems faces many methodological challenges. However, the performance evaluation of competing methods is limited by the small amount of publicly available data from biological experiments. Therefore, simulation studies with a realistic representation of the data…
Aarit Ahuja, Nadira Yusif Rodriguez, Alekh Karkada Ashok, Thomas Serre + 2 more
Visual simulation — i.e., using internal reconstructions of the world to experience potential future versions of events that are not currently happening — is among the most sophisticated capacities of the human mind. But is this ability in fact uniquely human? To answer this question, we tested monkeys on a series of…
Emma Wolpert, Kim Jelfs
Molecular cages contain an internal cavity designed to encapsulate other molecules, resulting in applications in molecular separation, gas storage, and catalysis. Introducing chirality in cage molecules can improve the selective separation of chiral molecules and add new functionalities due to the realisation of chiral…
Dan Spencer, Caitlin McKeown, David Tredwell, Benjamin Huckaby + 9 more
The development and use of virtual laboratories to augment traditional in-person skills training continues to grow. Virtual labs have been implemented in a number of diverse educational settings, which have many purported benefits including their adaptability, accessibility, and repeatability. However, few studies have…
Harold Fellermann, Ben Shirt-Ediss, Jerzy W. Koryza, Matthew Linsley + 2 more
Our PCR Simulator is a web-based application designed to introduce concepts of multi-factorial experimental design and support teaching of the polymerase chain reaction. Learners select experimental settings and receive results of their simulated reactions quickly, allowing rapid iteration between data generation and…
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Computing the free energy of protein-ligand binding by employing molecular dynamics (MD) simulations is becoming a valuable tool in the early stages of drug discovery. However, the cost and complexity of such simulations are often prohibitive for high-throughput studies. We present an automated workflow for the…
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In this article, we report a computational modeling study to enhance the understanding of the solvent-free extrusion process employed to produce filaments for the 3D printing of lithium-ion battery electrodes. Our study is supported by a newly developed dynamic 3D-resolved numerical model capable of simulating the…
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Computational simulations of biomolecules provide a wealth of information about the thermodynamic landscape of biologically important systems, kinetics of important cellular processes, and the biophysical basis of life. Despite the ubiquity of molecular simulations in biophysical literature, major challenges persist…
Alan Aspuru-Guzik, Roland Lindh, Markus Reiher
To date, the program for the development of methods and models for atomistic and continuum simulation directed toward chemicals and materials has reached an incredible degree of sophistication and maturity. Currently, one can witness an increasingly rapid emergence of advances in computing, artificial intelligence, and…
Simon Bennie, Kara Ranaghan, Helen Deeks, Heather Goldsmith + 3 more
The reemergence of virtual reality (VR) in the last few years has led to affordable commodity hardware that can offer new ways to teach, communicate and engage with difficult concepts, especially those which involve complicated 3D motion and spatial manipulation. In a higher education context, these immersive…
Alejandro A. Franco, Emilie Loup-Escande, Goran Loiseaux, Jean-Noël Chotard + 5 more
We present two digital-based serious games aiming to engage students and the general public with battery sciences. The first one is a multiscale simulator in Mixed Reality of a battery-powered Electric Vehicle (EV) interacting with an Electrical Grid. One of the players drives the EV in a Virtual Reality (VR)…