24 papers · ranked by Valyu relevance
Erik Recio-Armengol, Jens Eisert, Johannes Jakob Meyer
Quantum machine learning aims to improve learning methods through the use of quantum computers. If it is to ever realize its potential, many obstacles need to be overcome. A particularly pressing one arises at the prediction stage because the outputs of quantum learning models are inherently random. This creates an…
Konstantin Kharitonov, Masoud Mehrjoo, Mabel Ruiz-Lopez, Barbara Keitel + 7 more
'Barbara Keitel' 'Svea Kreis' 'Seung-gi Gang' 'Rui Pan' 'Alessandro Marras' 'Jonathan Correa' 'Cornelia B. Wunderer' 'Elke Plönjes'] In this work, single-shot ptychography was adapted to the XUV range and, as a proof of concept, performed at the free-electron laser FLASH at DESY to obtain a high-resolution…
Yingjia Lin, Shilin Huang, Kenneth R. Brown
For quantum error correction codes the required number of measurement rounds typically increases with the code distance when measurements are faulty. Single-shot error correction allows for an error threshold with only one round of noisy syndrome measurements regardless of the code size. Here we implement single-shot…
Xiaohan Kang, Bruce Hajek, Faqiang Wu, Yoshie Hanzawa
Many biological data sets are prepared using one-shot sampling, in which each individual organism is sampled at most once. Time series therefore do not follow trajectories of individuals over time. However, samples collected at different times from individuals grown under the same conditions share the same…
Giuseppe Lofano, Corey P. Mallett, Sylvie Bertholet, Derek T. O’Hagan
'Derek T. O’Hagan'] Vaccines represent the most successful medical intervention in history, with billions of lives saved. Although multiple doses of the same vaccine are typically required to reach an adequate level of protection, it would be advantageous to develop vaccines that induce protective immunity with fewer…
Inga Seidler, Tom Struck, Ran Xue, Niels Focke + 3 more
'Hendrik Bluhm' 'Lars R. Schreiber'] Small spin-qubit registers defined by single electrons confined in Si/SiGe quantum dots operate successfully and connecting these would permit scalable quantum computation. Shuttling the qubit carrying electrons between registers is a natural choice for high-fidelity coherent links…
Zhimin Wang, Min Li, Diru Wu, Jinchang Liu + 3 more
'Caimei Liu' 'Changgen Yang'] We will discuss an imaging measurement with a single photon sensitive and low noise camera aiming to a new paradigm in the optical readout of scintillation detectors. The features of the single photon sensitive camera will be characterized and demonstrated with a measurement on double-slit…
Nikite Mesvan
The use of Unmanned Aerial Vehicles (UAVs) as a substitute for ordinary vehicles in applications of search and rescue is being studied all over the world due to its flexible mobility and less obstruction, including two main tasks: search and rescue. This paper proposes an approach for the first task of searching and…
Zibang Zhang, Xueying Wang, Jingang Zhong
Fourier single-pixel imaging (FSI) has proven capable of reconstructing highquality two-dimensional and three-dimensional images. The utilization of the sparsity of natural images in Fourier domain allows high-resolution images to be reconstructed from far fewer measurements than effective image pixels. However…
ARIF ULLAH, Pavlo O. Dral
Nonadiabatic quantum dynamics are important for understanding light-harvesting processes, but their propagation with traditional methods can be rather expensive. Here we present a one-shot trajectory learning approach that allows to directly make ultra-fast prediction of the entire trajectory of the reduced density…
Humberto González‐Díaz, Lluís Martínez-León, Fernando Soldevila, Ma. Araiza-Esquivel + 2 more
'Ma. Araiza-Esquivel' 'Jesús Láncis' 'Enrique Tajahuerce'] Abstract: A single-pixel digital holography system with phase-encoded illumination using a digital micromirror device (DMD) as a spatial light modulator (SLM) is presented. The enhanced switching rate of DMDs, far exceeding the stringent frame-rate of liquid…
Authors not listed
The Single-probe is a multifunctional device that can be coupled to mass spectrometry (MS) for molecular analysis of microscale samples, such as single cells, tissue slices, and multicellular spheroids, under ambient conditions. In Single-probe single cell MS (SCMS) studies, this technique leverages direct sampling and…
Yu Wang, Zhi-Ying Guan, Shao-Wen Shi, Yi-Rong Jiang + 10 more
The shotgun proteomic analysis is currently the most promising single-cell protein sequencing technology, however its identification level of ∼1000 proteins per cell is still insufficient for practical applications. Here, we develop a pick-up single-cell proteomic analysis (PiSPA) workflow to achieve a deep…
Pallavi Gupta, Nandhini Balasubramaniam, Hwan-You Chang, Fan-Gang Tseng + 1 more
'Fan-Gang Tseng' 'Tuhin Subhra Santra'] The brain is an intricate network with complex organizational principles facilitating a concerted communication between single-neurons, distinct neuron populations, and remote brain areas. The communication, technically referred to as connectivity, between single-neurons, is the…
Authors not listed
Desorption Electrospray Ionization Mass Spectrometry Imaging (DESI-MSI) is a powerful technique for molecular analysis of surfaces; however, its application of single cell studies has not been previously published. In the current work, a commercial DESI setup (DESI XS) coupled to a mass spectrometer was used to analyze…
Shun Wu, Zhiqiang Yan, Cen Kong, Xia Li + 9 more
Monitoring neural population activity at single-cell resolution is essential for driving fundamental research and clinical innovations. However, translating advanced recording techniques from animal models to humans remains a significant challenge. Flexible neural electrodes have recently emerged as powerful tools for…
Siheun Lee, Hung M. Vu, Jung-Hyun Lee, Heejin Lim + 2 more
Simple Summary Cell-to-cell variation exists within a population of the same cell type due to stochastic gene and protein expression and environmental factors. Studying such cellular heterogeneity is the key to understanding the underlying mechanisms of fundamental biology and complex diseases, highly demanding…
T. Bednarski, E. Czerwiński, P. Moskal, P. Białas + 26 more
'Krzysztof Giergiel' 'Ł. Kapłon' 'Andrzej Kochanowski' 'G. Korcyl' 'Jakub Kowal' 'P. Kowalski' 'T. Kozik' 'W. Krzemień' 'Marcin Molenda' 'Ines Moskal' 'Szymon Niedźwiecki' 'M. Pałka' 'M. Pawlik-Niedźwiecka' 'L. Raczyński' 'Z. Rudy' 'P. Salabura' 'N.G. Sharma' 'M. Silarski' 'A. Słomski' 'Jerzy Smyrski' 'Adam Strzelecki'…
Nicola Luchi, Pamela Pinzani, Francesca Salvianti, Irene Mancini + 1 more
Single-cell technology is increasingly used to analyze the basis of molecular regulation and provide insights into different aspects of human diseases. Such technology is a breakthrough approach to study blood cancers by characterizing molecular information on a genome-wide scale at the single-cell level. These methods…
Juerg Straubhaar, Alexandria D’Souza, Zachary Niziolek, Bogdan Budnik
Single-cell analysis has clearly established itself in biology and biomedical fields as an invaluable tool that allows one to comprehensively understand the relationship between cells, including their types, states, transitions, trajectories, and spatial position. Scientific methods such as fluorescence labeling…
Lakmini Senavirathna, Cheng Ma, Ru Chen, Sheng Pan + 1 more
Dissecting the proteome of cell types and states at single-cell resolution, while being highly challenging, has significant implications in basic science and biomedicine. Mass spectrometry (MS)-based single-cell proteomics represents an emerging technology for system-wide, unbiased profiling of proteins in single…
Yi-Rong Jiang, Le Zhu, Lan-Rui Cao, Qiong Wu + 14 more
Nowadays, although single-cell multi-omics technologies are undergoing rapid development, simultaneous transcriptome and proteome analysis of a single-cell individual still faces great challenges. Here, we developed a single-cell simultaneous transcriptome and proteome (scSTAP) analysis platform based on microfluidics…
Authors not listed
Control over the charge of a nanoparticle (NP) in a radiofrequency ion trap is crucial for mass spectrometric and charge dependent investigations of single NPs. We show how this is achieved for positively charged silica NPs (nominal diameter 100 nm, 350–1400 e) with a simple experimental realization using a standard…
Harrison Specht, Edward Emmott, Aleksandra A. Petelski, R. Gray Huffman + 5 more
The fate and physiology of individual cells are controlled by protein interactions. Yet, our ability to quantitatively analyze proteins in single cells has remained limited. To overcome this barrier, we developed SCoPE2. It lowers cost and hands-on time by introducing automated and miniaturized sample preparation while…