25 papers · ranked by Valyu relevance
Yi Zhong, Xue-tao Jiang, Yong Yang, Ben-lian Xu + 3 more
'Lei Wang' 'Xin-feng Dong'] Structural topology optimization has gained widespread attention due to more possibilities of innovative structural design. The current research focus/hotspots, application areas, main research scholars, institutions and the countries involved in structural topology optimization are visually…
Keith J. Lee, Yijiang Huang, Caitlin Mueller
design optimization Authors: ['Keith J. Lee' 'Yijiang Huang' 'Caitlin Mueller'] Fast, gradient-based structural optimization has long been limited to a highly restricted subset of problems—namely, density-based compliance minimization—for which gradients can be analytically derived. For other objective functions…
Marek Tyburec, Jan Zeman, Martin Kružík, Didier Henrion
- b Departement of Physics, Faculty of Civil Engineering, Czech Technical University in Prague, Thákurova 7, 166 29 Prague 6, Czech Republic - c Institute of Information Theory and Automation, Czech Academy of Sciences, Pod vodárenskou věží 4, 182 08 Prague 8, Czech Republic - d LAAS-CNRS, University of Toulouse, 7…
Authors not listed
With the ever-increasing demand for atomistic structures representative of real-life systems as well as the ad-vent of exascale computers, it has now become necessary and possible to use advanced global optimization (GO) techniques to intelligently sample the potential energy surface (PES). Given the previous studies…
Rafael Merli, Antolín Martínez-Martínez, Juan José Ródenas, Marc Bosch-Galera + 1 more
'Marc Bosch-Galera' 'E. Nadal'] In the current industry, the development of optimized mechanical components able to satisfy the customer requirements evolves quickly. Therefore, companies are asked for efficient solutions to improve their products in terms of stiffness and strength. In this sense, Topology Optimization…
Gaoyuan Wu
Shape optimization is of great significance in structural engineering, as an efficient geometry leads to better performance of structures. However, the application of gradient-based shape optimization for structural and architectural design is limited, which is partly due to the difficulty and the complexity in…
Jyotiranjan nayak, Shafeequdheen P, Vijayakrishna Rowthu
This study investigates the impact of finite element selection on structural topology optimization using the SIMP (Solid Isotropic Material with Penalization) method. Specifically, it compares linear (P1) and quadratic (P2) triangular elements with the conventional bi-linear quadrilateral (Q1) elements. Numerical…
Odin Zhang, Jiaqi Wang, Tuscan Rock Thompson, Ziyi You + 3 more
Biomolecular interactions, including protein–protein interactions, protein–nucleic acid recognition, and protein–small molecule binding, underlie a wide range of biological processes and therapeutic mechanisms. Although recent de novo design methods can generate candidate binders for diverse molecular targets…
Eric Havenhill, Soham Ghosh
Cell migration requires the dynamic formation and dissolution of mechanical structures inside the cytoplasm. Stress fibers are made of F-actin during cell migration driven by the strategic localization of focal adhesion complexes at the cell-substrate interface. The nucleus is also strategically positioned in the cell…
Edwin P. Duque, Daniel Villarreal, Henrry Rojas A
The optimization of civil structures is a technique whose purpose is to efficiently use the materials that make up the structural systems based on previously established restrictions and objectives. The use and development of these techniques has been closely linked to technological advance since, through the use of…
Luis Saucedo-Mora, Ismael Ben-Yelun, Hugo García-Modet, Miguel Ángel Sanz-Gómez + 1 more
The design and manufacturing of high value industrial components is suffering a change of paradigm with 3D printing. In this change of paradigm, metamaterials have an important role because when a component is 3D-printed, it is performed from the micro level, where custom structures may be designed to endow the…
Bogdan Bochenek, Katarzyna Tajs-Zielińska
Although well-recognized in the fields of structural and material design and widely present in engineering literature, topology optimization still arouses a high interest within research communities. Moreover, it is observed that the development of innovative, efficient and versatile methods is one of the most…
Rizwan Azam, Muhammad Rizwan Riaz, Muhammad Umer Farooq, Faraz Ali + 4 more
'Muhammad Mohsan' 'Ahmed Farouk Deifalla' 'Abdeliazim Mustafa Mohamed' 'Pengcheng Jiao'] In the past, many studies have been conducted on the optimization of reinforced concrete (RC) structures. These studies have demonstrated the effectiveness of different optimization techniques to obtain an economical design.…
Meng-Han Zhang, Tao Gong
Evolution of sound systems of human language is an optimization process to improve communicative effectiveness: The intrinsic structures of sound systems are constantly organized with respect to constraints in speech production and perception. However, there lack sufficient quantitative descriptions of this process…
Dario Wirtz, Claus Horn
The vastness of the space of possible protein variations is often regarded an insurmountable challenge for effective optimization. Traditional approaches focus primarily on substitutions near the binding pocket but are frequently hindered by epistatic effects and non-convex optimization landscapes. Current AI-aided…
Authors not listed
This article presents an overview about the state of the art in the development of structured packings for distillation applications. The focus is on highlighting different approaches including heuristic development cycles, the development of new packing structures, 3D-printing as tool for manufacturing, and…
Tomasz Gajewski, Natalia Staszak, Tomasz Garbowski, Michele Bacciocchi
The production of thin-walled beams with various cross-sections is increasingly automated and digitized. This allows producing complicated cross-section shapes with a very high precision. Thus, a new opportunity has appeared to optimize these types of products. The optimized parameters are not only the lengths of the…
Reza Behrou, James K. Guest
This paper presents a topology optimization framework for structural problems subjected to transient loading. The mechanical model assumes a linear elastic isotropic material, infinitesimal strains, and a dynamic response. The optimization problem is solved using the gradient-based optimizer Method of Moving Asymptotes…
Mehran Ebrahimi, Hyunmin Cheong, Pradeep Kumar Jayaraman, Farhad Javid
'Farhad Javid'] In optimizing real-world structures, due to fabrication or budgetary restraints, the design variables may be restricted to a set of standard engineering choices. Such variables, commonly called categorical variables, are discrete and unordered in essence, precluding the utilization of gradient-based…
Mohammed Rady, Sameh Youssef Mahfouz, Andreas Lampropoulos
This paper investigates the effects of concrete grades and column spacings on the optimal design of reinforced concrete (RC) buildings. To this end, cost design optimization was performed for buildings with three different floor systems: flat plates (FS), flat slabs with drop panels (FSDP), and solid slabs (SS). The…
Junqi Wu, Liyan Dong, Nuo Jia, Longyi Li + 1 more
Direct Preference Optimization (DPO) has emerged as a powerful paradigm for aligning generative models, yet its temporal optimization dynamics in the discrete diffusion space of proteins remain poorly understood. Existing approaches often assume that maintaining structural integrity while optimizing physicochemical…
Shiyue Yang, Graeme Day
We describe the implementation of a Monte Carlo basin hopping global optimization procedure for the prediction of molecular crystal structure. The basin hopping method is combined with quasi-random structure generation in a hybrid method for crystal structure prediction, QR-BH, which combines the low-discrepancy…
Authors not listed
Photo-actuated organic crystals, which can be remotely controlled by light, are gaining attention as next-generation actuator materials. In the practical application of actuator materials, not only the mode of deformation but also the output force is an important property. Since the output force depends on both the…
Riley Hickman, Priyansh Parakh, Austin Cheng, Qianxiang Ai + 3 more
Experiment planning algorithms are a required component of autonomous platforms for scientific discovery. Selecting a suitable optimization algorithm for a novel application is an important yet difficult choice a researcher has to make based on past empirical performance on similar tasks. To facilitate the evaluation…
Riley Hickman, Matteo Aldeghi, Alán Aspuru-Guzik
Model-based optimization strategies, such as Bayesian optimization (BO), have been deployed across the natural sciences in design and discovery campaigns due to their sample efficiency and flexibility. The combination of such strategies with automated laboratory equipment and/or high-performance computing in a…