10 papers · ranked by Valyu relevance
Lorena de la Fuente, Ángeles Arzalluz-Luque, Manuel Tardáguila, Héctor del Risco + 12 more
'Héctor del Risco' 'Cristina Martí' 'Sonia Tarazona' 'Pedro Salguero' 'Raymond Scott' 'Alberto Lerma' 'Ana Alastrue-Agudo' 'Pablo Bonilla' 'Jeremy R. B. Newman' 'Shunichi Kosugi' 'Lauren M. McIntyre' 'Victoria Moreno-Manzano' 'Ana Conesa'] Recent advances in long-read sequencing solve inaccuracies in alternative…
Peter A. Durr, Kerryne Graham, Rieks D. van Klinken
The possibility that outbreaks of bluetongue (BT) and African horse sickness (AHS) might occur via long-distance wind dispersion (LDWD) of their insect vector (Culicoides spp.) was proposed by R. F. Sellers in a series of papers published between 1977 and 1991. These investigated the role of LDWD by means of visual…
Lorena de la Fuente, Ángeles Arzalluz-Luque, Manuel Tardáguila, Manuel Tardáguila + 11 more
Traditionally, the functional analysis of gene expression data has used pathway and network enrichment algorithms. These methods are usually gene rather than transcript centric and hence fall short to unravel functional roles associated to posttranscriptional regulatory mechanisms such as Alternative Splicing (AS) and…
Sofia Nogueira, Maria Alexandra Rodrigues, Ron Vender, Tiago Torres
Although topical drugs are the mainstay of treatment for patients with mild-to-moderate psoriasis, the developments observed in this field in the last two decades have been limited. The most commonly used drugs are still vitamin D analogues and corticosteroids, both with several limitations. The aryl hydrocarbon…
Pavol Bardy, Phuong M. Nguyen, Yan Liu, Matthew W. Craske + 6 more
Gene transfer agents (GTAs) are phage-derived elements that have evolved repeatedly across diverse prokaryotes, where they drive high-frequency horizontal gene transfer (HGT). Here, we demonstrate that the Rhodobacter capsulatus GTA (RcGTA) tailspike protein, TspA, is a potent biofilm-degrading enzyme. Purified TspA is…
G. I. Ogilvie
Astrophysical fluid bodies that orbit close to one another induce tidal distortions and flows that are subject to dissipative processes. The spin and orbital motions undergo a coupled evolution over astronomical timescales, which is relevant for many types of binary star, short-period extrasolar planetary systems and…
Shogo Yoshimoto, Atsuo Suzuki, Junichi Kanie, Kotaro Koiwai + 2 more
Trimeric autotransporter adhesin (TAA) is an outer membrane (OM) protein that is widely distributed in gram-negative bacteria and is involved primarily in adhesion to biotic and abiotic surfaces, cell agglutination, and biofilm formation. TAAs are secreted onto the OM by the type Vc secretion system (SS). Because the…
Fabio Giovannercole, Tom de Smet, Miguel Angel Vences-Guzmán, Frédéric Lauber + 8 more
In Proteobacteria, the outer membrane protein TamA and the inner membrane-anchored protein TamB form the Translocation and Assembly Module (TAM) complex, which facilitates the transport of autotransporters, virulence factors, and likely lipids across the two membranes. In Bacteroidetes TamA is replaced by TamL, a…
Alexander Muacevic, John R Adler, Eleni Klinaki, Adrianos Nezos + 3 more
'Athanasios G Tzioufas' 'Maria N Tsolia' 'Despoina N Maritsi'] A nine-year-old girl with a two-month history of fever and generalized malaise, along with intermittent abdominal pain, immigrant myalgia, throat pain, anorexia, and long-standing failure to thrive, was admitted to our department for further investigation…
Kristina Prus, Krystol Weidner, Caroline Alquist
Pediatric autoimmune neuropsychiatric disorders associated with streptococcal (PANDAS) infections and pediatric acute-onset neuropsychiatric syndrome (PANS) are typically diagnosed in childhood. Therapeutic plasma exchange (TPE) has been recommended to remove relevant antibodies and treat symptomatic presentations in…