26 papers · ranked by Valyu relevance
Preeti Sharma, Pradeep Kumar, Rachna Sharma, Vijaya Dhar Bhatt + 1 more
'PS Dhot'] Almost 30 years have passed since the term ‘tissue engineering’ was created to represent a new concept that focuses on the regeneration of neotissues from cells with the support of biomaterials and growth factors. This interdisciplinary engineering has attracted much attention as a new therapeutic means that…
Arthur J. Coury
In this article, an expansive interpretation of “Tissue Engineering” is proposed which is in congruence with classical and recent published definitions. I further simplify the definition of tissue engineering as: “Exerting systematic control of the body’s cells, matrices and fluids.” As a consequence, many medical…
Islam M. Adel, Mohamed F. ElMeligy, Nermeen A. Elkasabgy, Dong Keun Han
'Dong Keun Han'] Tissue regeneration is an auto-healing mechanism, initiating immediately following tissue damage to restore normal tissue structure and function. This falls in line with survival instinct being the most dominant instinct for any living organism. Nevertheless, the process is slow and not feasible in all…
Mojtaba Shafiei, Mohamed Nainar Mohamed Ansari, Saiful Izwan Abd Razak, Muhammad Umar Aslam Khan + 1 more
'Saiful Izwan Abd Razak' 'Muhammad Umar Aslam Khan' 'Ignazio Blanco'] Tissue engineering and regenerative medicine are generally concerned with reconstructing cells, tissues, or organs to restore typical biological characteristics. Liposomes are round vesicles with a hydrophilic center and bilayers of amphiphiles which…
Esam Bashir Yahya, A. A. Amirul, Abdul Khalil H.P.S., Niyi Gideon Olaiya + 5 more
'Niyi Gideon Olaiya' 'Muhammad Omer Iqbal' 'Fauziah Jummaat' 'Atty Sofea A.K.' 'A. S. Adnan' 'Young-Sam Cho'] The global transplantation market size was valued at USD 8.4 billion in 2020 and is expected to grow at a compound annual growth rate of 11.5% over the forecast period. The increasing demand for tissue…
María Cecilia Socci, Gabriela Rodríguez, Emilia Oliva, Shigeko Fushimi + 5 more
'Shigeko Fushimi' 'Kiyofumi Takabatake' 'Hitoshi Nagatsuka' 'Carmelo José Felice' 'Andrea Paola Rodríguez' 'Cornelia Kasper'] Tissue Engineering (TE) is an interdisciplinary field that encompasses materials science in combination with biological and engineering sciences. In recent years, an increase in the demand for…
Mariza Aires-Fernandes, Camila Fernanda Amantino, Stéphanie Rochetti do Amaral, Fernando Lucas Primo
Tissue engineering (TE) connects principles of life sciences and engineering to develop biomaterials as alternatives to biological systems and substitutes that can improve and restore tissue function. The principle of TE is the incorporation of cells through a 3D matrix support (scaffold) or using scaffold-free…
S. Sircar, J. N. Majumdar
Tissue Engineering (TE) is an interdisciplinary field dealing with the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function or a whole organ [52]. Currently, TE is emerging as an invaluable field of study and is one of the most…
Ali Bakhshinejad
The invention of three-dimensional printers has led to major innovations in tissue engineering. They have enabled the printing of complex geometries such as those that occur in natural tissues, that were not possible with traditional manufacturing techniques. Tissue engineering in particular deals with printing…
Chia-Wei Hsu, Terra Williams, Xiang Yu
3D printing has been applied to multiple areas since 1980. Biomedical applications have grown significantly and become the mainstream of 3D printing applications. In this review, we elucidated the publication distribution of biomedical 3D printing using the CAS Content Collection. From 2010 to 2021, journal and patent…
Alireza Shahin-Shamsabadi, John Cappuccitti
Scaffold-free tissue engineering enables the construction of biomimetic tissues and organs by preserving cell-cell and cell-matrix interactions while avoiding exogenous scaffolds and biomaterials. Yet current approaches are limited to thin sheets or simple spheroids and often lack cellular maturity and organized…
Elcin Nizami Huseyn
Tissue engineering technology and tissue cell-based stem cell research have made great strides in treating tissue and organ damage, correcting tissue and organ dysfunction, and reducing surgical complications. In the past, traditional methods have used biological substitutes for tissue repair materials, while tissue…
Sarah K. Van Houten, Michael T. K. Bramson, David T. Corr
Bioreactors are commonly used to apply biophysically-relevant stimulations to tissue-engineered constructs in order to explore how these stimuli influence tissue development, healing, and homeostasis. These bioreactors offer great flexibility as key features of the stimuli (e.g., duty cycle, frequency, amplitude…
Alexander W. Justin, Federico Cammarata, Andrew A. Guy, Silas R. Estevez + 8 more
There is a significant need across multiple indications for an off-the-shelf bioengineered tubular graft which fulfils the mechanical and biological requirements for implantation and function but does not necessarily require cells for manufacture or deployment. Herein, we present a tissue-like tubular construct using a…
Levin Hafa, Louise Breideband, Lucas Ramirez Posada, Núria Torras + 3 more
This research introduces a new 3D bioprinter that incorporates live imaging of the bioprinted tissue with high resolution and high-speed capabilities. The printer employs a light sheet-based system to photocrosslink polymers into hydrogels at a printing speed of up to 0.66 mm³/s with a resolution of 15.7 µm. A…
Zhai Hongfeng, Qiu Changhong, Jin Jun, Shao Xin
In this article we investigated the preparation of tissue-engineered urethra by using the urethral epithelial subculture cells of male New Zealand young rabbits. We inoculated the epithelial cells of urinary mucosa of male New Zealand young rabbits on collagen, chitosan and collagen chitosan composite as scaffolds to…
Iain Muntz, Michele Fenu, Gerjo J.V.M. van Osch, Gijsje H. Koenderink
'Gijsje H. Koenderink'] Abstract: Living tissue is able to withstand large stresses in everyday life, yet it also actively adapts to dynamic loads. This remarkable mechanical behaviour emerges from the interplay between living cells and their non-living extracellular environment. Here we review recent insights into the…
Daniel J. Modulevsky, Charles M. Cuerrier, Andrew E. Pelling
There is intense interest in developing novel biomaterials which support the invasion and proliferation of living cells for potential applications in tissue engineering and regenerative medicine. Decellularization of existing tissues have formed the basis of one major approach to producing 3D scaffolds for such…
Rémy Gauthier, Christophe Jeannin, Nina Attik, Ana-Maria Trunfio-Sfarghiu + 2 more
'Ana-Maria Trunfio-Sfarghiu' 'Kerstin Gritsch' 'Brigitte Grosgogeat'] Abstract: The periodontal biomechanical environment is very difficult to investigate. By the complex geometry and composition of the periodontal ligament, its mechanical behavior is very dependent on the type of loading (compressive vs. tensile…
Mariane Martinez, Robert L. Witt, Mary C. Farach-Carson, Daniel A. Harrington
Complex branched salivary structures remain challenging to replicate within implant ready hydrogels. We showed previously that hyaluronic acid (HA)-based hydrogels enable growth and organization of primary salivary-derived human stem/progenitor cells (hS/PCs) into multicellular spheroids. Here, we systematically…
Mahmoud Sesa, Hagen Holthusen, Lukas Lamm, Christian Böhm + 3 more
'Tim Brepols' 'Stefan Jockenhövel' 'Stefanie Reese'] Abstract. The development of tissue-engineered cardiovascular implants can improve the lives of large segments of our society who suffer from cardiovascular diseases. Regenerative tissues are fabricated using a process called tissue maturation. Furthermore, it is…
Authors not listed
Self-organizing tissues, such as organoids, offer transformative potential beyond healthcare by enabling the sustainable production of advanced materials. Resource scarcity and global warming drive the need for innovative fabrication solutions. This prospective review explores developmental biology as a manufacturing…
David González-Martínez, Mabel Barreiro Carpio, Aidee Arizpe Tafoya, Eduardo González-Martínez + 2 more
Extrusion 3D bioprinting is a technology that allows the deposition of cells within hydrogels in well-defined spatial patterns, facilitating the fabrication of tissue biomimetics. Gelatin methacrylate (GelMA)-based hydrogels are biocompatible, biodegradable, and promote cell adhesion and proliferation, which makes them…
Noor Abu Jarad, Jeffrey I Weitz, Tohid Didar
Improving the performance of blood-contacting medical implants is a global health necessity aimed at reducing mortality and morbidity in patients with cardiovascular diseases. Surface modification of the biomaterials from which the implants are constructed has been used to reduce the risk of complications such as…
Moein Zarei, Marek J. Żwir, Beata Michalkiewicz, Miroslawa El Fray
Fabricating complex hierarchical structures mimicking natural vessels and arteries is pivotal for addressing problems of cardiovascular diseases. Various fabrication strategies have been explored to achieve this goal, each contributing unique advantages and challenges to the development of functional vascular grafts.…
Ritambhara Dash, Abhay Kumar Rajak, Ramagiri Praveen Kumar, Parameshwar Kommu + 3 more
Bio ceramics have enormous applications in the medical field as being used as implants. The base material in bioceramics is mostly calcium phosphate which comes in the form of hydroxyapatite (HAp) or Beta-tricalcium phosphate (β-TCP). The other materials are silica and alumina. The different blends of these bioceramics…