23 papers · ranked by Valyu relevance
Peter Aleström, Livia D’Angelo, Paul J Midtlyng, Daniel F Schorderet + 3 more
'Stefan Schulte-Merker' 'Frederic Sohm' 'Susan Warner'] This article provides recommendations for the care of laboratory zebrafish (Danio rerio) as part of the further implementation of Annex A to the European Convention on the protection of vertebrate animals used for experimental and other scientific purposes, EU…
David M Parichy
Over the last two decades, the zebrafish has joined the ranks of premier model organisms for biomedical research, with a full suite of tools and genomic resources. Yet we still know comparatively little about its natural history. Here I review what is known about the natural history of the zebrafish, where significant…
Daniel Castranova, Bakary Samasa, Marina Venero Galanternik, Aniket V. Gore + 1 more
The zebrafish has become a widely used animal model due in large part to its accessibility to and usefulness for high-resolution optical imaging. Although zebrafish research has historically focused mostly on early development, in recent years the fish has increasingly been used to study regeneration, cancer…
José G. Ortiz, Robert Gerlai
Life on Earth started just over 3.5 billion years ago. The last common ancestor of current-day fish and mammals lived about 0.4 billion years ago. That is, the first 3.1 billion years of biological evolution are shared between these two vertebrate taxa. The result of this long common evolutionary history is that there…
Federica Tonon, Gabriele Grassi
Belonging to the family of Cyprinidae, the zebrafish is a small freshwater fish present in the rivers of Bangladesh, Northern India and Southern Nepal [1]. Active during the day, in the wild, zebrafish feed on small aquatic invertebrates. Their use as a model organism to investigate novel therapeutic molecules as well…
Jaanus Suurväli, Andrew R Whiteley, Yichen Zheng, Karim Gharbi + 2 more
The zebrafish (Danio rerio) is a model vertebrate widely used to study disease, development and other aspects of vertebrate biology. Most of the research is performed on laboratory strains, one of which has been fully sequenced in order to derive a reference genome. It is known that the laboratory strains differ…
Jeffrey R. Kelly, Sierra G. Shelton, Danita K. Daniel, Anuradha Bhat + 9 more
'Rubina Mondal' 'Fahren Nipple' 'Halima Amro' 'Myra E. Bower' 'Gabriel Isaac' 'Gillian McHaney' 'Emilia P. Martins' 'Delia S. Shelton' 'Markus Brinkmann'] Environmental change poses a devastating risk to human and environmental health. Rapid assessment of water conditions is necessary for monitoring, evaluating, and…
Jana Oltova, Jindrich Jindrich, Ctibor Skuta, Ondrej Svoboda + 2 more
Small fish species, like zebrafish or medaka, are constantly gaining popularity in basic research and disease modeling as a useful alternative to rodent model organisms. However, the tracking options for fish within a facility are rather limited. Here, we present an aquatic species tracking database, Zebrabase…
Yvonne M. Bradford, Ceri E. Van Slyke, Douglas G. Howe, David Fashena + 10 more
Danio rerio is a model organism used to investigate vertebrate development. Manipulation of the zebrafish genome and resultant gene products by mutation or targeted knockdown has made the zebrafish a good system for investigating gene function, providing a resource to investigate genetic contributors to phenotype and…
Christopher J. Lambert, Briana C. Freshner, Arlen Chung, Tamara J. Stevenson + 5 more
'Tamara J. Stevenson' 'D. Miranda Bowles' 'Raheel Samuel' 'Bruce K. Gale' 'Joshua L. Bonkowsky' 'Zilong Wen'] Zebrafish are a valuable model organism in biomedical research. Their rapid development, ability to model human diseases, utility for testing genetic variants identified from next-generation sequencing, amenity…
Qianghua Chen, Huiyu Wang, Li Ming, Ying Zhao
Zebrafish share a high degree of homology with human genes and are commonly used as model organism in biomedical research. For medical laboratories, counting zebrafish is a daily task. Due to the tiny size of zebrafish, manual visual counting is challenging. Existing counting methods are either not applicable to small…
Kevin Adi Kurnia, Gilbert Audira, Michael Edbert Suryanto, Tzong-Rong Ger + 1 more
Zebrafish (Danio rerio) are widely used in neurobehavioral research due to their translational relevance in studying fear. Eight different fish species and variations were tested to induce fear responses in zebrafish, including one positive control (convict cichlid, Amatitlania nigrofasciata) and negative control…
Malte Pedersen, Joakim Bruslund Haurum, Stefan Hein Bengtson, Thomas B. Moeslund
'Thomas B. Moeslund'] In this work we present a novel publicly available stereo based 3D RGB dataset for multi-object zebrafish tracking, called 3D-ZeF. Zebrafish is an increasingly popular model organism used for studying neurological disorders, drug addiction, and more. Behavioral analysis is often a critical part of…
Monica Gomes Lima, Herculano Anderson Manoel, Caio Maximino
Important neurochemical variations between strains or linages which correlate with behavioral differences have been identified in different species. Here, we report neurochemical and behavioral differences in four common zebrafish wild-type strains (blue shortfin, longfin stripped, leopard and albino). leo zebrafish…
John E Dowling
These two stories illustrate the usefulness of zebrafish as a model organism for studying visual mechanisms ([f2-jovr-07-97]). Combining physiology with behavior coupled with genetics and fast development provides a powerful approach. Figure 2: Figure 2. The zebrafish, Danio rerio, is an important vertebrate model…
Axel Séguret, Bertrand Collignon, Léo Cazenille, Yohann Chemtob + 1 more
'José Halloy'] We explore the collective behaviours of 7 group sizes: 1, 2, 3, 5, 7, 10 and 20 AB zebrafish (Danio rerio) in a constraint environment composed of two identical squared rooms connected by a corridor. This simple set-up is similar to a natural patchy environment. We track the positions and the identities…
Bertrand Collignon, Axel Séguret, José Halloy
Collective motion is one of the most ubiquitous behaviours displayed by social organisms and has led to the development of numerous models. Recent advances in the understanding of sensory system and information processing by animals impel to revise classical assumptions made in decisional algorithms. In this context…
Wenbin Yang, Yutong Meng, Danyang Li, Quan Wen
Larval zebrafish is a promising vertebrate model for understanding neural mechanisms underlying learning and memory. Here, we report on a high-throughput operant learning system for zebrafish larvae and demonstrate that lower visual intensity ratio of the conditioned stimulus to the background can enhance learning…
Axel Séguret, Bertrand Collignon, José Halloy
Recent studies show differences in individual motion and shoaling tendency between strains of the same species. Here, we analyse the collective motion and the response to visual stimuli in two morphologically different strains (TL and AB) of zebrafish. For both strains, we observe 10 groups of 5 and 10 zebrafish…
Bryan James, Alexander Medvedev, Sergei Makarov, Robert Nelson + 2 more
Popularized on social media, hand-moldable plastics are formed by consumers into tools, trinkets, and dental prosthetics. Despite the anticipated dermal and oral contact, manufacturers share little information with consumers about these materials. Inherent to their function, moldable plastics pose a risk of dermal and…
Authors not listed
The development of effective neurological treatments remains a challenge due to the low permeation across the blood-brain barrier (BBB). The use of nanoparticles for brain drug delivery is promising, but the level of BBB crossing remains low, typically around 0.5-3%. We report the synthesis of negatively charged…
Claudius F. Kratochwil, Muktai Kuwalekar, Jan Haege, Nidal Karagic
At the core of most research in zoological disciplines, ranging from developmental biology to genetics to behavioral biology, is the ability to keep animals in captivity. While facilities for traditional model organisms often benefit from well-established designs, construction of a facility for less commonly studied…
Raja Mohanrao, Clyde S. Pinto, Andrejus Suchenko, Guy J. Clarkson + 4 more
A series of clickable single-benzene-based fluorophores derived from tetrafluoroterephthalonitrile (4F-2CN) is reported. Fluorophores based on a tetrahydroquinoxaline skeleton (2F-2CN-(β-NH2Ala)) exhibited improved photophysical properties owing to better planarity and conjugation over those with dihydro[1,4]thiazine…