Inflammation between defense and disease: impact on tissue repair and chronic sickness Inflammation between defense and disease

Abstract

Inflammatory disorders underlie a vast variety of human diseases. If one of the main components of the immune system is disturbed (soluble mediators or cells), the entire inflammatory process will be abnormal, due to the cascade activation of the following factors. Beside the classical inflammatory diseases, a lot of other human pathologies have been shown to be initiated and sustained by the inflammatory processes. This group of diseases is clearly associated with abnormalities of the immune system and a disturbed inflammatory response: autoimmune diseases, chronical infections (glomeruloneph